Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829333 | 0.92 | POLB (0.53) | L3MBTL1POLBHTR3EHTR3BADRB1 | |
| SCHEMBL19520761 | 0.88 | POLB (0.52) | L3MBTL1POLBHTR3EHTR3BADRB1 | |
| SCHEMBL738227 | 0.84 | HTR3E (0.59) | L3MBTL1POLBHTR3EHTR3BADRB1 | |
| SCHEMBL5820022 | 0.82 | POLB (0.50) | L3MBTL1POLBHTR3EHTR3BADRB1 | |
| SCHEMBL3182863 | 0.79 | HTR3E (0.53) | L3MBTL1POLBHTR3EHTR3BADRB1 | |
| SCHEMBL9828629 | 0.78 | ADRB1 (0.51) | POLBADRB1MAPTTSHRALDH1A1 | |
| SCHEMBL9831116 | 0.74 | ADRB1 (0.55) | POLBADRB1MAPTKMT2AMEN1 | |
| SCHEMBL28599511 | 0.72 | HTR3E (0.73) | L3MBTL1POLBHTR3EHTR3BADRB1 | |
| SCHEMBL29656856 | 0.72 | HTR3E (0.73) | L3MBTL1POLBHTR3EHTR3BADRB1 | |
| SCHEMBL10534863 | 0.72 | EED (0.58) | MAPTKMT2ARAB9AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017189553-A1 | REMOVAL OF SENESCENCE-ASSOCIATED MACROPHAGES | EVERON BIOSCIENCES, INC. (US) | 2017-11-02 | — | — | WO | disclosed |