Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829333 | 0.90 | POLB (0.53) | POLBHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL3182863 | 0.87 | HTR3E (0.53) | POLBHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL12301330 | 0.83 | ALOX5 (0.56) | ADRB1MAPTKMT2ATSHRMEN1 | |
| SCHEMBL19545461 | 0.82 | L3MBTL1 (0.49) | POLBHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL21262494 | 0.81 | ADRB1 (0.44) | ADRB1MAPTHSD17B10KMT2ARAB9A | |
| SCHEMBL14638126 | 0.80 | KCNA5 (0.42) | POLBMAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL19520761 | 0.79 | POLB (0.52) | POLBHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL738227 | 0.79 | HTR3E (0.59) | POLBHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL2925759 | 0.78 | HTR3E (0.68) | POLBHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL28129519 | 0.78 | HTR3E (0.68) | POLBHTR3EHTR3BADRB1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135383-A2 | INDAZOLES | MYRIAD GENETICS, INC. (US) | 2006-12-21 | — | — | WO | disclosed |