SCHEMBL195537

SCHEMBL195537

S=c1c2ccccc2oc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
KDM4E B2RXH2 5/20 0.56
MAOA P21397 5/20 0.56
MAPT P10636 4/20 0.56
HPGD P15428 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
GLA P06280 1/20 0.56
CYP3A4 P08684 1/20 0.56
PGAM1 P18669 1/20 0.56
CASP1 P29466 1/20 0.56
CASP7 P55210 1/20 0.56
HSD17B10 Q99714 1/20 0.56
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
AHR P35869 2/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 1/20 0.46
GAA P10253 2/20 0.41
NQO1 P15559 1/20 0.41
MAOB P27338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29487286 1.00 ALDH1A1 (0.56) ALDH1A1KDM4EMAOAMAPTHPGD
Dibenzofuran SCHEMBL9868133 0.82 MAPT (0.68) ALDH1A1KDM4EMAOAMAPTHPGD
Dibenzofuran SCHEMBL29635704 0.82 MAPT (0.68) ALDH1A1KDM4EMAOAMAPTHPGD
Dibenzofuran SCHEMBL8207 0.82 MAPT (0.68) ALDH1A1KDM4EMAOAMAPTHPGD
SCHEMBL6436055 0.82 MAOA (0.64) ALDH1A1KDM4EMAOAMAPTHPGD
SCHEMBL11634806 0.82 GABRP (0.45) ALDH1A1KDM4EMAOAMAPTHPGD
SCHEMBL1258329 0.82 MAOB (0.50) ALDH1A1KDM4EMAOAMAPTHPGD
SCHEMBL11573807 0.82 TNKS (0.45) ALDH1A1KDM4EMAOAMAPTHPGD
SCHEMBL17115265 0.82 IDO1 (0.43) ALDH1A1KDM4EMAOAMAPTHPGD
SCHEMBL9851903 0.82 AHR (0.47) ALDH1A1KDM4EMAOAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 818 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058557-A Method for preparing beta-ketonitrile compound by photocatalysis of isoxazole ring opening 南京工业大学 2025-05-30 CN claimed
CN-119859262-A High-temperature-resistant protective layer and preparation method and application thereof 复旦大学 2025-04-22 CN claimed
CN-119798753-A Preparation process of photo-curing organosilicon release film 江门市领昱电子材料有限公司 2025-04-11 CN claimed
CN-119431226-A Preparation method of visible light catalytic beta-aryl beta-pyridylalkyl ketone compound 国科大杭州高等研究院 2025-02-14 CN claimed
CN-119409678-A Novel bisphenol fluorene-like high-refraction compound 江苏集萃光敏电子材料研究所有限公司 2025-02-11 CN claimed
CN-116354857-B Preparation method of beta-amino sulfone and derivative thereof 中国人民解放军海军军医大学 2025-01-21 CN claimed
CN-118930860-A Preparation method of polymer containing sulfonyl and sulfonic acid 太原理工大学 2024-11-12 CN claimed
CN-118791455-A Synthetic method for preparing 3, 4-dichloro coumarin from 4-chloro coumarin 广西大学 2024-10-18 CN claimed
CN-118459307-A Synthesis method of 4, 5-disubstituted high-cubane compound 湖南师范大学 2024-08-09 CN claimed
CN-118307410-A Preparation method of chiral secondary alcohol compound 武汉大学 2024-07-09 CN claimed
WO-2006091464-A1 IMPROVED TIME/ TEMPERATURE INDICATORS SUN CHEMICAL CORPORATION (US) 2006-08-31 WO claimed
WO-2006060281-A2 CATIONICALLY CURABLE COATING COMPOSITIONS SUN CHEMICAL LIMITED (GB) 2006-06-08 WO claimed
EP-0924523-B1 Method and diagnostic means for the detection of haemostatic disorders DADE BEHRING MARBURG GMBH (DE) 2006-06-07 EP claimed
US-6750032-B2 DETECTION OF BLOOD COAGULATION DEFECTS; OBTAIN BLOOD SAMPLE, INCUBATE WITH MODULATOR, MONITOR COAGULATION AND DISSOLUTION, EVALUATE FOR DEFECTS DADE BEHRING MARBURG GMBH (DE) 2004-06-15 US claimed
US-6649351-B2 Detecting a target nucleic acid sequence in sample; obtain nucleotide sequences sample, incubate with nuclease, detect repoter molecule label ACLARA BIOSCIENCES, INC. 2003-11-18 US claimed
US-20030092012-A1 Methods for detecting a plurality of analytes by chromatography MONOGRAM BIOSCIENCES, INC. 2003-05-15 US claimed
US-20030027235-A1 Novel method and diagnostic agent for hemostasis diagnosis DADE BEHRING MARBURG GMBH (DE) 2003-02-06 US claimed
US-20020150927-A1 Methods for detecting a plurality of analytes by mass spectrometry MONOGRAM BIOSCIENCES, INC. 2002-10-17 US claimed
US-6187594-B1 MIXING SAMPLE AND AT LEAST TWO SUBSTANCES WHICH INTERACT WITH EACH OTHER, AT LEAST ONE SUBSTANCE BINDS TO THE BLOOD CLOT; MEASURING SIGNAL; CORRELATING WITH DEGREE OF PLATELET AGGREGATION, CLOT FORMATION AND/OR CLOT DISSOLUTION DADE BEHRING MARBURG GMBH (DE) 2001-02-13 US claimed
EP-0924523-A2 Method and diagnostic means for the detection of haemostatic disorders Dade Behring Marburg GmbH (DE) 1999-06-23 EP claimed