Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | TKT | P29401 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPP5C | P53041 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2949884 | 0.79 | TKT (0.69) | HSP90AA1TKTKDM4ETDP1PPP5C | |
| Hydrochloric Acid SCHEMBL14637039 | 0.78 | HSP90AA1 (0.61) | HSP90AA1TKTKDM4ETDP1PPP5C | |
| SCHEMBL13741567 | 0.78 | TKT (0.68) | HSP90AA1TKTKDM4ETDP1PPP5C | |
| Hydrochloric Acid SCHEMBL18879467 | 0.77 | HSP90AA1 (0.60) | HSP90AA1TKTKDM4ETDP1PPP5C | |
| Hydrochloric Acid SCHEMBL5940670 | 0.75 | HSP90AA1 (0.57) | HSP90AA1TKTKDM4ETDP1PPP5C | |
| Hydrochloric Acid SCHEMBL4355811 | 0.74 | TKT (0.70) | HSP90AA1TKTKDM4ETDP1PPP5C | |
| SCHEMBL13741845 | 0.73 | TKT (0.71) | HSP90AA1TKTKDM4ETDP1PPP5C | |
| Thiamine Ion SCHEMBL10074 | 0.70 | HSP90AA1 (0.98) | HSP90AA1TKTKDM4ETDP1LMNA | |
| Thiamine Ion SCHEMBL7090274 | 0.70 | HSP90AA1 (0.98) | HSP90AA1TKTKDM4ETDP1LMNA | |
| Thiamine Ion SCHEMBL29445547 | 0.70 | HSP90AA1 (0.98) | HSP90AA1TKTKDM4ETDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11692207-B2 | Enzymatic methods for butanol production | NEWPEK S.A. DE C.V. (MX) | 2023-07-04 | — | — | US | disclosed |
| US-20210222209-A1 | ENZYMATIC METHODS FOR BUTANOL PRODUCTION | NEWPEK S.A. DE C.V. (MX) | 2021-07-22 | — | — | US | disclosed |
| EP-3452606-A1 | ENZYMATIC METHODS FOR BUTANOL PRODUCTION | Newpek S.A. De C.V. (MX) | 2019-03-13 | — | — | EP | disclosed |
| CN-103913440-B | A kind of pyruvate dehydrogenase complex enzyme activity detection reagent and its application | 北京中科非凡生物技术有限公司 | 2018-01-23 | — | — | CN | disclosed |
| WO-2017191483-A1 | ENZYMATIC METHODS FOR BUTANOL PRODUCTION | NEWPEK S.A. DE C.V. (MX) | 2017-11-09 | — | — | WO | disclosed |