Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554377 | 0.89 | SMN1; SMN2 (0.51) | MAPTCYP1A2CYP3A4CYP2C19LMNA | |
| SCHEMBL19554374 | 0.89 | KDM4E (0.49) | MAPTCYP1A2CYP3A4CYP2C19LMNA | |
| SCHEMBL19554232 | 0.88 | MAPT (0.45) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19554220 | 0.84 | KDM4E (0.42) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19554361 | 0.80 | HDAC1 (0.41) | MAPTCYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL19554101 | 0.80 | CYP1A2 (0.45) | MAPTCYP1A2CYP3A4CYP2C19LMNA | |
| SCHEMBL19555285 | 0.79 | NPC1 (0.45) | MAPTCYP1A2CYP2C19LMNAMEN1 | |
| SCHEMBL19554930 | 0.78 | GPR35 (0.42) | MAPTCYP1A2CYP3A4CYP2C19LMNA | |
| SCHEMBL19554329 | 0.77 | MAPT (0.59) | MAPTCYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL19554380 | 0.77 | MAOB (0.39) | MAPTCYP1A2CYP3A4CYP2C19TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |