Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554232 | 0.92 | MAPT (0.45) | KDM4ENPSR1MEN1LMNAMAPT | |
| SCHEMBL19554361 | 0.91 | HDAC1 (0.41) | KDM4ENPSR1MEN1LMNAMAPT | |
| SCHEMBL19554377 | 0.91 | SMN1; SMN2 (0.51) | KDM4ENPSR1MEN1LMNAMAPT | |
| SCHEMBL19555285 | 0.90 | NPC1 (0.45) | KDM4ENPSR1MEN1LMNAMAPT | |
| SCHEMBL19554142 | 0.89 | MAPT (0.49) | KDM4ENPSR1MEN1LMNAMAPT | |
| SCHEMBL19554220 | 0.88 | KDM4E (0.42) | KDM4ENPSR1MEN1LMNAMAPT | |
| SCHEMBL19554279 | 0.86 | JAK2 (0.42) | MEN1MAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL19554871 | 0.82 | F10 (0.48) | MEN1KMT2ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL19554101 | 0.81 | CYP1A2 (0.45) | KDM4EMEN1LMNAMAPTKMT2A | |
| SCHEMBL19554191 | 0.81 | GAA (0.47) | KDM4ENPSR1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |