Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554374 | 0.91 | KDM4E (0.49) | HDAC1HDAC8HDAC6KDM4ENPSR1 | |
| SCHEMBL19554930 | 0.89 | GPR35 (0.42) | HDAC6KDM4EKMT2AMAPTNPC1 | |
| SCHEMBL19554279 | 0.85 | JAK2 (0.42) | HDAC1KMT2AMAPTNPC1MEN1 | |
| SCHEMBL19555285 | 0.83 | NPC1 (0.45) | HDAC1HDAC8HDAC6KDM4ENPSR1 | |
| SCHEMBL19554232 | 0.83 | MAPT (0.45) | KDM4ENPSR1TP53KMT2AMAOB | |
| SCHEMBL19554377 | 0.82 | SMN1; SMN2 (0.51) | KDM4ENPSR1TP53KMT2AMAOB | |
| SCHEMBL19554871 | 0.80 | F10 (0.48) | KMT2ANPC1MEN1CYP1A2CYP2C9 | |
| SCHEMBL19554142 | 0.80 | MAPT (0.49) | KDM4ENPSR1TP53KMT2AMAOB | |
| SCHEMBL19554101 | 0.80 | CYP1A2 (0.45) | KDM4ETP53KMT2AMAPTNPC1 | |
| SCHEMBL19554191 | 0.80 | GAA (0.47) | KDM4ENPSR1TP53KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |