Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554279 | 0.89 | JAK2 (0.42) | GAAJAK2JAK1NPC1RAB9A | |
| SCHEMBL19554191 | 0.86 | GAA (0.47) | GAANPC1RAB9A | |
| SCHEMBL19554220 | 0.85 | KDM4E (0.42) | GAANPC1 | |
| SCHEMBL19554871 | 0.84 | F10 (0.48) | JAK2JAK1NPC1RAB9A | |
| SCHEMBL19554313 | 0.84 | KCNMA1 (0.42) | JAK2JAK1NPC1RAB9AHDAC1 | |
| SCHEMBL19554306 | 0.82 | MEN1 (0.42) | JAK2JAK1NPC1RAB9A | |
| SCHEMBL19554711 | 0.80 | MAPT (0.42) | RAB9A | |
| SCHEMBL19554319 | 0.80 | SMN1; SMN2 (0.44) | SERPINE1GAAJAK2JAK1NPC1 | |
| SCHEMBL19554849 | 0.77 | GAA (0.40) | GAAJAK2JAK1NPC1RAB9A | |
| SCHEMBL19554374 | 0.77 | KDM4E (0.49) | NPC1RAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |