Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554279 | 0.95 | JAK2 (0.42) | GAAF10NPC1RAB9AMEN1 | |
| SCHEMBL19554313 | 0.90 | KCNMA1 (0.42) | F10NPC1RAB9ARXFP1MAPT | |
| SCHEMBL19554871 | 0.90 | F10 (0.48) | F10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL19554306 | 0.87 | MEN1 (0.42) | F10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL19554160 | 0.86 | SERPINE1 (0.42) | GAANPC1RAB9A | |
| SCHEMBL19554319 | 0.85 | SMN1; SMN2 (0.44) | GAAF10NPC1RAB9AMEN1 | |
| SCHEMBL19554711 | 0.85 | MAPT (0.42) | F10RAB9AMEN1KMT2AMAPT | |
| SCHEMBL19554849 | 0.82 | GAA (0.40) | GAAF10NPC1RAB9ARXFP1 | |
| SCHEMBL19554374 | 0.81 | KDM4E (0.49) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL19554361 | 0.80 | HDAC1 (0.41) | NPC1RAB9AMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |