Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554191 | 0.95 | GAA (0.47) | F10GAACA2CA9RAB9A | |
| SCHEMBL19554313 | 0.93 | KCNMA1 (0.42) | JAK2JAK1F10RAB9ANPC1 | |
| SCHEMBL19554871 | 0.93 | F10 (0.48) | JAK2JAK1F10RAB9ANPC1 | |
| SCHEMBL19554319 | 0.90 | SMN1; SMN2 (0.44) | JAK2JAK1F10GAARAB9A | |
| SCHEMBL19554306 | 0.90 | MEN1 (0.42) | JAK2JAK1F10RAB9ANPC1 | |
| SCHEMBL19554160 | 0.89 | SERPINE1 (0.42) | JAK2JAK1GAARAB9ANPC1 | |
| SCHEMBL19554711 | 0.88 | MAPT (0.42) | F10RAB9ACYP1A2CYP2C19CYP2D6 | |
| SCHEMBL19554374 | 0.86 | KDM4E (0.49) | RAB9ANPC1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL19554849 | 0.85 | GAA (0.40) | JAK2JAK1F10GAARAB9A | |
| SCHEMBL19554361 | 0.85 | HDAC1 (0.41) | RAB9ANPC1CYP1A2CYP2C19HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |