Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.56 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.53 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554172 | 0.90 | DHODH (0.52) | DHODHSLC16A3NPC1RAB9AGAA | |
| SCHEMBL19554234 | 0.90 | DHODH (0.58) | DHODHSLC16A3NPC1RAB9AGAA | |
| SCHEMBL19554323 | 0.86 | DHODH (0.68) | DHODHMEN1KMT2AMAPTPKM | |
| SCHEMBL19554221 | 0.86 | KMT2A (0.64) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL1307456 | 0.85 | GRIK1 (0.67) | DHODHSLC16A3MEN1KMT2APKM | |
| SCHEMBL19554207 | 0.84 | RAB9A (0.52) | DHODHSLC16A3NPC1RAB9AGAA | |
| SCHEMBL19554169 | 0.83 | DHODH (0.56) | DHODHSLC16A3NPC1RAB9AGAA | |
| SCHEMBL19554175 | 0.83 | F2 (0.47) | DHODHSLC16A3NPC1RAB9AMEN1 | |
| SCHEMBL8044197 | 0.82 | DHODH (0.79) | DHODHSLC16A3NPC1RAB9AMEN1 | |
| SCHEMBL6357745 | 0.80 | DHODH (0.78) | DHODHSLC16A3NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |