Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BCL9 | O00512 | 2/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554215 | 0.91 | SMN1; SMN2 (0.44) | SMN1; SMN2ALBKDM4EALDH1A1HPGD | |
| SCHEMBL19554419 | 0.85 | BCL6 (0.42) | GRM5KAT2BBAZ2BMEN1KMT2A | |
| SCHEMBL19554182 | 0.83 | NPC1 (0.42) | SMN1; SMN2ALBPDE4DBCL9CTNNB1 | |
| SCHEMBL19554093 | 0.81 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL19554233 | 0.79 | HDAC3 (0.41) | SMN1; SMN2KDM4EALDH1A1HPGDGRM5 | |
| SCHEMBL19554225 | 0.79 | SERPINE1 (0.43) | SERPINE1SMN1; SMN2ALBKDM4EALDH1A1 | |
| SCHEMBL19554290 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL19554240 | 0.78 | STING1 (0.50) | ALBKDM4EMEN1NPC1RAB9A | |
| SCHEMBL19554330 | 0.78 | KCNK2 (0.46) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL19554194 | 0.77 | PDE5A (0.39) | ALBGRM5BCL9CTNNB1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |