SCHEMBL19554245

SCHEMBL19554245

N#Cc1cc(C(=O)O)c(N)cc1OCC1CC1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
XDH P47989 6/20 0.48
MAP4K4 O95819 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19554301 0.86 KDM4E (0.48) XDH
SCHEMBL23908984 0.82 XDH (0.46) XDH
SCHEMBL19554261 0.82 XDH (0.46) XDHMAP4K4
SCHEMBL5230406 0.79 MAP4K4 (0.41) MAP4K4
SCHEMBL6483619 0.77 ALDH1A1 (0.47)
SCHEMBL1017998 0.75 XDH (0.63) XDHMAP4K4
SCHEMBL7266033 0.75 HTR4 (0.44)
SCHEMBL23909023 0.75 MEN1 (0.42) XDH
SCHEMBL19554358 0.75 MAPK8 (0.36) XDH
SCHEMBL5231117 0.74 MAP4K4 (0.44) XDHMAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017192304-A1 ARYLCARBOXAMIDES AND USES THEREOF INCEPTION 1, INC. (US) 2017-11-09 WO disclosed