Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PRSS12 | P56730 | 6/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554217 | 0.82 | SERPINE1 (0.58) | KCNK2KCNK10 | |
| SCHEMBL19554172 | 0.81 | DHODH (0.52) | PRSS12ACLYF10MEN1KMT2A | |
| SCHEMBL19554330 | 0.81 | KCNK2 (0.46) | HDAC1PRSS12ACLYSTING1KCNK2 | |
| SCHEMBL19554350 | 0.76 | F2 (0.44) | PRSS12ACLYSTING1MEN1KMT2A | |
| SCHEMBL19554240 | 0.76 | STING1 (0.50) | HDAC1PRSS12ACLYSTING1KCNK2 | |
| SCHEMBL2273546 | 0.76 | ACLY (0.58) | NAMPTHDAC1HDAC8HDAC6PRSS12 | |
| SCHEMBL2271954 | 0.73 | CTNNB1 (0.47) | NAMPTPRSS12ACLYMEN1KMT2A | |
| SCHEMBL2271921 | 0.73 | MEN1 (0.55) | NAMPTHDAC1HDAC8HDAC6PRSS12 | |
| SCHEMBL19554265 | 0.73 | SERPINE1 (0.58) | KCNK2KCNK10 | |
| SCHEMBL13201004 | 0.71 | NAMPT (0.71) | NAMPTHDAC1HDAC8HDAC6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |