Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.36 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.34 |
| ▸ | ILK | Q13418 | 1/20 | 0.32 |
| ▸ | S100B | P04271 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554817 | 0.84 | — | — | |
| SCHEMBL19554924 | 0.84 | NPC1 (0.45) | S100BNR1I2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9730064 | 0.81 | PPOX (0.40) | TIPARPROCK2NR1I2FLT3CYP2C9 | |
| SCHEMBL19554342 | 0.76 | TRAP1 (0.30) | — | |
| SCHEMBL1944696 | 0.75 | KCNH2 (0.38) | ROCK2ALDH1A1 | |
| SCHEMBL19554937 | 0.73 | PPOX (0.40) | ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL5906062 | 0.71 | MGLL (0.47) | HTR7ALDH1A1 | |
| SCHEMBL9620476 | 0.70 | ALDH1A1 (0.48) | NR1I2CYP2C9ALDH1A1 | |
| SCHEMBL9730624 | 0.70 | ALDH1A1 (0.44) | NR1I2CYP2C9ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL1943984 | 0.70 | MEN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |