Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977258 | 0.83 | MAPT (0.44) | TLR8MAPT | |
| SCHEMBL8599860 | 0.82 | TLR8 (0.49) | ALDH1A1SMN1; SMN2KMT2ATLR8MEN1 | |
| SCHEMBL19554342 | 0.77 | TRAP1 (0.30) | — | |
| SCHEMBL19554375 | 0.76 | LMNA (0.51) | TSHRALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL19555155 | 0.76 | BACE1 (0.39) | CYP3A4ALDH1A1KMT2AMEN1 | |
| SCHEMBL19554817 | 0.75 | — | — | |
| SCHEMBL5905977 | 0.74 | GAA (0.42) | IDO1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL19554924 | 0.74 | NPC1 (0.45) | TSHRALDH1A1SMN1; SMN2TDP1KMT2A | |
| SCHEMBL3239509 | 0.73 | IDO1 (0.46) | IDO1CYP3A4ALDH1A1 | |
| SCHEMBL1943984 | 0.73 | MEN1 (0.35) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |