Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.41 |
| ▸ | RPA1 | P27694 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977258 | 0.88 | MAPT (0.44) | TLR8KDM4EHTTL3MBTL1MAPT | |
| SCHEMBL9730218 | 0.84 | TLR8 (0.38) | TLR8KDM4EHTT | |
| SCHEMBL1943803 | 0.84 | MEN1 (0.39) | TLR8KMT2AMEN1GAAMARS1 | |
| SCHEMBL19554366 | 0.82 | CTDSP1 (0.49) | TLR8ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9730328 | 0.81 | HCAR1 (0.38) | TLR8HCAR1NOTUM | |
| SCHEMBL8599859 | 0.80 | MARS1 (0.39) | HTTL3MBTL1NPSR1ALDH1A1KMT2A | |
| SCHEMBL1249223 | 0.80 | L3MBTL1 (0.44) | TLR8L3MBTL1LMNAALOX12NPSR1 | |
| SCHEMBL5905865 | 0.79 | MGLL (0.43) | KDM4EALDH1A1MAPTHCAR1CDK4 | |
| SCHEMBL19554375 | 0.77 | LMNA (0.51) | L3MBTL1LMNANPSR1ALDH1A1KMT2A | |
| SCHEMBL9730122 | 0.77 | GRIN2D (0.41) | TLR8HTTL3MBTL1KMT2AHCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058491-C | Tetrazoline series compound with herbicide activity | NIPPON BAYER PESTICIDE CO LTD (JP) | 2000-11-15 | — | — | CN | disclosed |
| US-5767286-A | REACTING A TETRAZOLINONE WITH A CARBAMOYL CHLORIDE IN THE PRESENCE OF 4-DIMETHYLAMINOPYRIDINE | NIHON BAYER AGROCHEM K. K. (JP) | 1998-06-16 | — | — | US | disclosed |
| EP-0646577-B1 | Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones | BAYER AGROCHEM KK (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0643049-B1 | A process for the preparation of 1-substituted-5(4H)-tetrazolinones | BAYER AGROCHEM KK (JP) | 1997-05-14 | — | — | EP | disclosed |
| CN-1130182-A | Tetrazoline series compound with herbicide activity | NIPPON BAYER PESTICIDE CO LTD (JP) | 1996-09-04 | — | — | CN | disclosed |
| EP-0708097-A1 | Herbicidally active tetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5502204-A | REACTING WITH ETHYLENE OXIDE DERIVATIVE | NIHON BAYER AGROCHEM K.K. (JP) | 1996-03-26 | — | — | US | disclosed |
| EP-0646577-A1 | Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1995-04-05 | — | — | EP | disclosed |
| EP-0643049-A1 | A process for the preparation of 1-substituted-5(4H)-tetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1995-03-15 | — | — | EP | disclosed |