Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599860 | 0.88 | TLR8 (0.49) | MAPTHTTCDK4CCND1TLR8 | |
| SCHEMBL19554366 | 0.83 | CTDSP1 (0.49) | MAPTTLR8 | |
| SCHEMBL9730328 | 0.82 | HCAR1 (0.38) | TLR8NOTUM | |
| SCHEMBL8977289 | 0.82 | NPSR1 (0.46) | MAPTHTTCDK4CCND1KDM4E | |
| SCHEMBL5905865 | 0.81 | MGLL (0.43) | MAPTCDK4CCND1KDM4E | |
| SCHEMBL1944383 | 0.81 | HTT (0.47) | MAPTHTTADRA1B | |
| SCHEMBL19554375 | 0.79 | LMNA (0.51) | MAPTL3MBTL1 | |
| SCHEMBL9730122 | 0.78 | GRIN2D (0.41) | HTTTLR8L3MBTL1 | |
| SCHEMBL10369675 | 0.77 | HSP90AA1 (0.40) | TLR8 | |
| SCHEMBL8686630 | 0.77 | TIPARP (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708097-A1 | Herbicidally active tetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1996-04-24 | — | — | EP | disclosed |