Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 3/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADH5 | P11766 | 1/20 | 0.36 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889340 | 0.88 | GRIK1 (0.47) | GRIK1KMOFTOTBK1ALDH1A1 | |
| SCHEMBL6710242 | 0.81 | IDO1 (0.49) | IDO1GRIK1KMOTBK1ALDH1A1 | |
| SCHEMBL5695123 | 0.81 | GRIK1 (0.42) | GRIK1KMOFTOF11KLKB1 | |
| SCHEMBL2892854 | 0.78 | GRIK1 (0.50) | GRIK1KMOF11KLKB1ALDH1A1 | |
| SCHEMBL6530898 | 0.77 | ALDH1A1 (0.45) | IDO1FTOTBK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1947739 | 0.75 | KMO (0.44) | GRIK1KMOFTOTBK1ALDH1A1 | |
| SCHEMBL19554382 | 0.74 | TBK1 (0.36) | GRIK1KMOFTOTBK1ALDH1A1 | |
| SCHEMBL12548091 | 0.73 | ALDH1A1 (0.37) | GRIK1KMOFTOTBK1ALDH1A1 | |
| SCHEMBL18603158 | 0.73 | ALDH1A1 (0.57) | KMOALDH1A1ADH5 | |
| SCHEMBL19554932 | 0.73 | NPC1 (0.45) | KMOFTOTBK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |