Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23054258 | 0.86 | S1PR5 (0.57) | ALDH1A1MAPK1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL19778180 | 0.86 | HPGD (0.44) | ALDH1A1MAPK1L3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL26452696 | 0.85 | CPB1 (0.45) | LTA4HALDH1A1MAPK1L3MBTL1CPB1 | |
| SCHEMBL23734315 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL19966271 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL18746181 | 0.81 | CPB1 (0.43) | ALDH1A1MAPK1L3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL630153 | 0.81 | SMN1; SMN2 (0.60) | ALDH1A1HTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL14446963 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPK1L3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL6616917 | 0.80 | S1PR5 (0.60) | LTA4HALDH1A1HPGDMAPTNPSR1 | |
| SCHEMBL15447240 | 0.80 | POLB (0.51) | ALDH1A1MAPK1L3MBTL1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180016265-A1 | AMINOESTER DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-01-18 | — | — | US | disclosed |
| US-9809582-B2 | Aminoester derivatives | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180016265-A1 | AMINOESTER DERIVATIVES | PDE4A, PDE3A, PDE3B | LTA4H 40/4885ALDH1A1 351/4885MAPK1 2470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.