Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13435254 | 0.90 | TDP1 (0.51) | ALDH1A1MAPTHPGDCYP2C9CYP1A2 | |
| SCHEMBL24189141 | 0.86 | FDPS (0.47) | ALDH1A1MAPTHPGDCYP2C9CYP1A2 | |
| SCHEMBL10123080 | 0.84 | LMNA (0.48) | ALDH1A1MAPTHPGDCYP2C9CYP1A2 | |
| SCHEMBL13230081 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDCYP2C9CYP1A2 | |
| SCHEMBL19557489 | 0.83 | TDP1 (0.57) | ALDH1A1SMN1; SMN2LMNATDP1NPC1 | |
| SCHEMBL19557494 | 0.81 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDCYP2C9CYP1A2 | |
| SCHEMBL19878350 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDCYP2C9CYP1A2 | |
| SCHEMBL13435255 | 0.76 | TDP1 (0.64) | ALDH1A1SMN1; SMN2LMNATDP1NPC1 | |
| SCHEMBL12530343 | 0.76 | FDPS (0.41) | ALDH1A1MAPTHPGDCYP2C9CYP1A2 | |
| SCHEMBL14654319 | 0.73 | TDP1 (0.47) | ALDH1A1MAPTHPGDCYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9810700-B1 | Fluorogenic calcium ion indicators and methods of using the same | AAT BIOQUEST, INC. (US) | 2017-11-07 | — | — | US | disclosed |
| US-9810700-B1 | Fluorogenic calcium ion indicators and methods of using the same | AAT BIOQUEST, INC. (US) | 2017-11-07 | — | — | US | disclosed |