Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.41 |
| ▸ | TCF4 | P15884 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20683082 | 0.86 | HPGD (0.65) | SMN1; SMN2HPGDALDH1A1OPRL1MEN1 | |
| SCHEMBL20821457 | 0.82 | RAB9A (0.42) | SMN1; SMN2HPGDALDH1A1OPRL1MEN1 | |
| SCHEMBL4597359 | 0.80 | ALDH1A1 (0.53) | SMN1; SMN2HPGDALDH1A1OPRL1MEN1 | |
| SCHEMBL1170649 | 0.79 | KDM4E (0.52) | SMN1; SMN2HPGDALDH1A1NPSR1NPC1 | |
| SCHEMBL6261732 | 0.79 | SMN1; SMN2 (0.75) | SMN1; SMN2HPGDALDH1A1OPRL1MEN1 | |
| SCHEMBL17076824 | 0.79 | ALDH1A1 (0.51) | SMN1; SMN2HPGDALDH1A1OPRL1MEN1 | |
| SCHEMBL11098104 | 0.78 | HPGD (0.47) | SMN1; SMN2HPGDALDH1A1OPRL1MEN1 | |
| SCHEMBL3828091 | 0.78 | OPRL1 (0.60) | SMN1; SMN2HPGDALDH1A1OPRL1MEN1 | |
| SCHEMBL1101910 | 0.76 | CYP2C19 (0.54) | SMN1; SMN2HPGDALDH1A1MEN1MAPT | |
| SCHEMBL10847753 | 0.76 | RAB9A (0.47) | SMN1; SMN2HPGDALDH1A1OPRL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11552266-B2 | Electrodes for electronic devices comprising an organic semiconducting layer | FLEXENABLE LIMITED (GB) | 2023-01-10 | — | — | US | disclosed |
| US-20200274086-A1 | ELECTRODES FOR ELECTRONIC DEVICES COMPRISING AN ORGANIC SEMICONDUCTING LAYER | FLEXENABLE LIMITED (GB) | 2020-08-27 | — | — | US | disclosed |
| US-9809545-B2 | Factor XIa inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-11-07 | — | — | US | disclosed |