SCHEMBL20683082

SCHEMBL20683082

CSc1nc2ccc(F)cc2[nH]1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
ALDH1A1 P00352 1/20 0.65
ALPL P05186 1/20 0.51
ALPI P09923 1/20 0.51
ALPG P10696 1/20 0.51
TCF4 P15884 1/20 0.51
CTNNB1 P35222 1/20 0.51
AMY1A P0DUB6 9/20 0.50
METAP2 P50579 2/20 0.49
METAP1 P53582 2/20 0.49
CBFB Q13951 1/20 0.49
IDO1 P14902 1/20 0.49
CYP11B1 P15538 1/20 0.48
OPRL1 P41146 1/20 0.47
MEN1 O00255 1/20 0.45
TTR P02766 1/20 0.45
HSP90AA1 P07900 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19558136 0.86 SMN1; SMN2 (0.51) HPGDSMN1; SMN2ALDH1A1TCF4CTNNB1
SCHEMBL20821455 0.82 IDO1 (0.53) HPGDSMN1; SMN2ALDH1A1ALPLALPI
SCHEMBL4597364 0.80 ALDH1A1 (0.67) HPGDSMN1; SMN2ALDH1A1METAP2METAP1
SCHEMBL8667804 0.79 HPGD (1.00) HPGDSMN1; SMN2ALDH1A1AMY1AMETAP2
SCHEMBL2593902 0.79 ALDH1A1 (0.65) HPGDSMN1; SMN2ALDH1A1MEN1MAPT
SCHEMBL11098109 0.78 HPGD (0.59) HPGDSMN1; SMN2ALDH1A1CBFBMAPT
SCHEMBL3828091 0.78 OPRL1 (0.60) HPGDSMN1; SMN2ALDH1A1CBFBOPRL1
SCHEMBL7672276 0.76 CYP2E1 (0.70) HPGDSMN1; SMN2ALDH1A1
SCHEMBL17085004 0.76 HPGD (0.61) HPGDSMN1; SMN2ALDH1A1METAP2
SCHEMBL29438978 0.76 ALDH1A1 (0.61) HPGDSMN1; SMN2ALDH1A1ALPLALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11552266-B2 Electrodes for electronic devices comprising an organic semiconducting layer FLEXENABLE LIMITED (GB) 2023-01-10 US disclosed
US-20200274086-A1 ELECTRODES FOR ELECTRONIC DEVICES COMPRISING AN ORGANIC SEMICONDUCTING LAYER FLEXENABLE LIMITED (GB) 2020-08-27 US disclosed
US-10189830-B2 Alkyl-heteroaryl substituted quinone derivatives for treatment of oxidative stress disorders BIOELECTRON TECHNOLOGY CORPORATION (US) 2019-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10189830-B2 Alkyl-heteroaryl substituted quinone derivatives for treatment of oxidative stress disorders NQO1, COQ8A, NDUFAB1 HPGD 217/4885SMN1; SMN2 303/4885ALDH1A1 605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.