Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25074186 | 0.86 | TSHR (0.38) | ALDH1A1KMT2AKDM4EMAPTHDAC3 | |
| SCHEMBL13759768 | 0.83 | ALDH1A1 (0.36) | ALDH1A1KMT2AMAPTHDAC3HDAC4 | |
| SCHEMBL28546869 | 0.83 | ALDH1A1 (0.36) | ALDH1A1KMT2AKDM4EMAPTHDAC3 | |
| SCHEMBL25695856 | 0.80 | CA1 (0.46) | ALDH1A1KMT2AKDM4EMAPTCRBN | |
| SCHEMBL19370781 | 0.78 | CA1 (0.40) | ALDH1A1KMT2AKDM4EMAPTCRBN | |
| SCHEMBL11860524 | 0.78 | HDAC8 (0.52) | ALDH1A1KDM4EHDAC3HDAC4HDAC1 | |
| SCHEMBL23553380 | 0.78 | LMNA (0.43) | ALDH1A1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL18723202 | 0.77 | FAAH (0.53) | ALDH1A1KMT2AMEN1FAAHMAPK1 | |
| SCHEMBL17804496 | 0.77 | CTSD (0.54) | ALDH1A1KMT2AKDM4EMAPTHDAC3 | |
| SCHEMBL16133498 | 0.75 | SMN1; SMN2 (0.47) | ALDH1A1KMT2AKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9809571-B2 | Deoxyuridine triphosphatase inhibitors | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-11-07 | — | — | US | disclosed |