Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 5/20 | 0.48 |
| ▸ | MMP3 | P08254 | 7/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18721777 | 0.89 | TAS2R14 (0.55) | TAS2R14RORCMMP3MMP2MMP13 | |
| SCHEMBL13265885 | 0.86 | TAS2R14 (0.52) | TAS2R14RORCMMP3MMP2MMP13 | |
| SCHEMBL19558612 | 0.84 | TAS2R14 (0.54) | TAS2R14RORCMMP3MMP2MMP13 | |
| SCHEMBL19558622 | 0.76 | KMT2A (0.35) | RORCALDH1A1KMT2ALMNA | |
| SCHEMBL8276256 | 0.75 | MMP2 (0.58) | TAS2R14MMP2MMP13ALDH1A1LMNA | |
| SCHEMBL12734386 | 0.74 | TAS2R14 (0.46) | TAS2R14RORCMMP3MMP2MMP13 | |
| SCHEMBL15737599 | 0.73 | SPPL2A (0.60) | LMNA | |
| SCHEMBL13770738 | 0.71 | CA1 (0.49) | TAS2R14MMP3 | |
| SCHEMBL15759123 | 0.71 | TAS2R14 (0.54) | TAS2R14RORCMMP3MMP2MMP13 | |
| SCHEMBL20258639 | 0.71 | RORC (0.57) | TAS2R14RORCMMP3MMP2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9808527-B2 | Methods and compositions for treating HIV infections | PURDUE RESEARCH FOUNDATION (US) | 2017-11-07 | — | — | US | disclosed |