Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.58 |
| ▸ | MMP13 | P45452 | 2/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13463174 | 0.84 | MMP2 (0.60) | MMP2MMP13KEAP1NFE2L2LMNA | |
| SCHEMBL18721777 | 0.78 | TAS2R14 (0.55) | MMP2MMP13KEAP1NFE2L2HTT | |
| SCHEMBL13265885 | 0.76 | TAS2R14 (0.52) | MMP2MMP13LMNAALDH1A1TAS2R14 | |
| SCHEMBL14338879 | 0.76 | MMP2 (0.51) | MMP2MMP13KEAP1NFE2L2LMNA | |
| SCHEMBL2582258 | 0.75 | KEAP1 (0.50) | MMP2MMP13KEAP1NFE2L2LMNA | |
| SCHEMBL19558708 | 0.75 | TAS2R14 (0.51) | MMP2MMP13LMNAALDH1A1TAS2R14 | |
| SCHEMBL2576422 | 0.75 | MMP2 (0.48) | MMP2MMP13KEAP1NFE2L2LMNA | |
| SCHEMBL13825586 | 0.74 | MMP2 (0.46) | MMP2MMP13KEAP1NFE2L2LMNA | |
| SCHEMBL5983203 | 0.74 | SPPL2A (0.67) | MMP2MMP13KEAP1NFE2L2LMNA | |
| SCHEMBL12156755 | 0.74 | SPPL2A (0.67) | MMP2MMP13KEAP1NFE2L2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2422780-A1 | Resistance-repellent retroviral protease inhibitors | Sequoia Pharmaceuticals, Inc. (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-2422781-A1 | Resistance-repellent retroviral protease inhibitors | Sequoia Pharmaceuticals, Inc. (US) | 2012-02-29 | — | — | EP | disclosed |
| WO-2005110428-A2 | RESISTANCE-REPELLENT RETROVIRAL PROTEASE INHIBITORS | SEQUOIA PHARMACEUTICALS, INC. (US) | 2005-11-24 | — | — | WO | disclosed |