SCHEMBL1955893

SCHEMBL1955893

Cc1ccccc1-c1nccn1S(N)(=O)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
FLT1 P17948 1/20 0.42
CDK8 P49336 1/20 0.42
CDK9 P50750 1/20 0.42
LIMK1 P53667 1/20 0.42
ROCK1 Q13464 1/20 0.42
CLK4 Q9HAZ1 1/20 0.42
PTGS2 P35354 3/20 0.39
PTGS1 P23219 2/20 0.39
CA5A P35218 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
POLB P06746 1/20 0.35
FFAR2 O15552 1/20 0.35
BRD4 O60885 1/20 0.35
RAPGEF4 Q8WZA2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8190241 0.75 CLK4 (0.49) FLT1CDK8CDK9LIMK1ROCK1
SCHEMBL288348 0.75 CA2 (0.39) CA1CA2CA12CA9PTGS2
SCHEMBL13587950 0.72 BRD4 (0.56) FLT1CDK8CDK9LIMK1ROCK1
SCHEMBL19353774 0.71 CYP3A4 (0.50) FLT1CDK8CDK9LIMK1ROCK1
SCHEMBL28175124 0.71 POLB (0.45) CA1CA2CA12CA9POLB
SCHEMBL23417079 0.71
SCHEMBL9618397 0.69 FLT1 (0.46) FLT1CDK8CDK9LIMK1ROCK1
SCHEMBL8636455 0.69 ESR1 (0.45) CA1CA2CA12CA9FLT1
SCHEMBL12797926 0.68 FLT1 (0.45) FLT1CDK8CDK9LIMK1ROCK1
SCHEMBL12797931 0.68 FLT1 (0.49) FLT1CDK8CDK9LIMK1ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104582487-B The method for controlling insect 先正达参股股份有限公司 2019-05-31 CN disclosed
EP-2922837-A1 INSECTICIDAL COMPOUNDS BASED ON N-(ARYLSULFANYLMETHYL) CARBOXAMIDE DERIVATIVES Syngenta Participations AG (CH) 2015-09-30 EP disclosed
EP-2922831-A1 PESTICIDAL COMPOUNDS BASED ON ARYLTHIOSULFONAMIDE DERIVATIVES Syngenta Participations AG (CH) 2015-09-30 EP disclosed
EP-2917201-A1 DIHYDROTHIOPHENE DERIVATIVES AS INSECTICIDAL COMPOUNDS Syngenta Participations AG (CH) 2015-09-16 EP disclosed
EP-2887802-A2 METHODS OF SOIL PEST CONTROL Syngenta Participations AG (CH) 2015-07-01 EP disclosed
EP-2887809-A1 METHODS OF CONTROLLING INSECTS Syngenta Participations AG (CH) 2015-07-01 EP disclosed
EP-2887810-A1 METHODS OF CONTROLLING INSECTS Syngenta Participations AG (CH) 2015-07-01 EP disclosed
WO-2014079935-A9 INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2014-09-04 WO disclosed
EP-2748155-A1 ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS Syngenta Participations AG (CH) 2014-07-02 EP disclosed
EP-2747570-A1 ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS Syngenta Participations AG (CH) 2014-07-02 EP disclosed
WO-2011151199-A1 SPIROHETEROCYCLIC PYRROLIDINE DERIVATIVES BASED PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2011-12-08 WO disclosed
EP-2369934-A1 SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES Syngenta Participations AG (CH) 2011-10-05 EP disclosed
EP-2352376-A1 SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES Syngenta Participations AG (CH) 2011-08-10 EP disclosed
WO-2011067240-A1 SPIRO FUSED 1 -AMINO - PIPERIDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY SYNGENTA PARTICIPATIONS AG (CH) 2011-06-09 WO disclosed
WO-2011067135-A1 SPIRO FUSED 1 -AMINO - PIPERIDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY SYNGENTA PARTICIPATIONS AG (CH) 2011-06-09 WO disclosed
WO-2011067131-A1 SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2011-06-09 WO disclosed
WO-2011067203-A1 CHEMICAL COMPOUNDS AND THEIR USE AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2011-06-09 WO disclosed
CN-101940214-A Control the Spiropiperidine derivatives of insect SYNGENTA PARTICIPATIONS AG 2011-01-12 CN disclosed
WO-2010066780-A1 SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2010-06-17 WO disclosed
WO-2010063670-A1 SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2010-06-10 WO disclosed