SCHEMBL195600

SCHEMBL195600

CC(C)(O)C(=O)c1ccc(Br)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
GSK3B P49841 2/20 0.45
LMNA P02545 3/20 0.44
RAB9A P51151 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 2/20 0.44
MAPK1 P28482 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
OGG1 O15527 1/20 0.43
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11298330 0.88 CA2 (0.46) CES2CES1CA2LMNAHDAC1
SCHEMBL725519 0.84 CES2 (0.54) CES2CES1CA1CA2GSK3B
SCHEMBL3050432 0.84 CES2 (0.54) CES2CES1CA1CA2GSK3B
SCHEMBL11772991 0.84 CES2 (0.54) CES2CES1CA1CA2GSK3B
SCHEMBL4419639 0.81 ALDH1A1 (0.50) CA2LMNAMAPTALDH1A1HTT
SCHEMBL10943093 0.81 CES2 (0.50) CES2CES1CA2RAB9A
SCHEMBL15251658 0.81 RXRA (0.44) CA1CA2RAB9AMAPTNPC1
SCHEMBL4656447 0.80 CES2 (0.62) CES2CES1CA1CA2GSK3B
SCHEMBL10701118 0.79 CA2 (0.41) CES2CES1CA2LMNAMAPK1
SCHEMBL129749 0.79 ESR1 (0.50) CES2CA1CA2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240317942-A1 THIOL-CONTAINING COMPOSITION, PHOTOSETTING COMPOSITION, AND THERMOSETTING COMPOSITION RESONAC CORPORATION (JP) 2024-09-26 US disclosed
EP-4375302-A1 THIOL-CONTAINING COMPOSITION, PHOTOCURABLE COMPOSITION, AND THERMOSETTING COMPOSITION Resonac Corporation (JP) 2024-05-29 EP disclosed
CN-117651722-A Thiol-containing composition, photocurable composition, and thermosetting composition 株式会社力森诺科 2024-03-05 CN disclosed
WO-2023003011-A1 THIOL-CONTAINING COMPOSITION, PHOTOCURABLE COMPOSITION, AND THERMOSETTING COMPOSITION 昭和電工株式会社 2023-01-26 WO disclosed
CN-110105314-B Method for preparing feloxicib 江苏君若药业有限公司 2022-05-17 CN disclosed
CN-104641295-B Photosensitive resin composition for photospacer and photospacer 株式会社日本触媒 2020-03-03 CN disclosed
US-8772048-B2 Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems KENT STATE UNIVERSITY (US) 2014-07-08 US disclosed
US-8772048-B2 Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems KENT STATE UNIVERSITY (US) 2014-07-08 US disclosed
US-8772048-B2 Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems KENT STATE UNIVERSITY (US) 2014-07-08 US disclosed
US-8753801-B2 Photosensitive composition, pattern forming material, and photosensitive film, pattern forming method, pattern film, low refractive index film, optical device and solid-state imaging device each using the same FUJIFILM CORPORATION (JP) 2014-06-17 US disclosed
WO-2006046736-A1 THIOL COMPOUND AND PHOTOSENSITIVE COMPOSITION USING THE SAME SHOWA DENKO K.K. (JP) 2006-05-04 WO disclosed
US-20060036023-A1 Color filter black matrix resist composition SHOWA DENKO K.K. (JP) 2006-02-16 US disclosed
EP-1573397-A1 COLOR FILTER BLACK MATRIX RESIST COMPOSITION Showa Denko K.K. (JP) 2005-09-14 EP disclosed
US-20050153231-A1 Thiol compound, photopolymerization initiator composition and photosensitive composition SHOWA DENKO K.K. (JP) 2005-07-14 US disclosed
EP-1478668-A2 THIOL COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPOSITION AND PHOTOSENSITIVE COMPOSITION Showa Denko K.K. (JP) 2004-11-24 EP disclosed
WO-2004055596-A1 COLOR FILTER BLACK MATRIX RESIST COMPOSITION SHOWA DENKO K. K. (JP) 2004-07-01 WO disclosed
WO-2003072614-A2 THIOL COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPOSITION AND PHOTOSENSITIVE COMPOSITION SHOWA DENKO K.K. (JP) 2003-09-04 WO disclosed
EP-1141952-A1 UV-RADIATION-HARDENABLE BINDER COMPOSITION FOR MAGNETIC RECORDING MEDIA AND PHOTOINITIATOR MIXTURE EMTEC Magnetics GmbH (DE) 2001-10-10 EP disclosed
WO-2000028531-A1 UV-RADIATION-HARDENABLE BINDER COMPOSITION FOR MAGNETIC RECORDING MEDIA AND PHOTOINITIATOR MIXTURE EMTEC MAGNETICS GMBH (DE) 2000-05-18 WO disclosed
EP-0446175-A2 Mixture of photoinitiators CIBA-GEIGY AG (CH) 1991-09-11 EP disclosed