Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18507891 | 0.85 | CA1 (0.60) | PPARGCA1CA2CA9KMT2A | |
| SCHEMBL3884174 | 0.83 | ACHE (0.56) | PPARGACHEHTTTDP1L3MBTL1 | |
| SCHEMBL29468643 | 0.83 | ACHE (0.56) | PPARGACHEHTTTDP1L3MBTL1 | |
| SCHEMBL4599461 | 0.82 | PPARG (0.58) | PPARGACHEHTTTDP1L3MBTL1 | |
| SCHEMBL167959 | 0.81 | PPARG (0.54) | PPARGACHEHTTTDP1L3MBTL1 | |
| SCHEMBL1532691 | 0.80 | LMNA (0.53) | PPARGACHEHTTTDP1L3MBTL1 | |
| SCHEMBL9451450 | 0.80 | CA2 (0.73) | PPARGACHECA1CA2CA9 | |
| SCHEMBL11164410 | 0.80 | PPARG (0.53) | PPARGACHEHTTTDP1L3MBTL1 | |
| SCHEMBL17318098 | 0.80 | CA1 (0.50) | ACHELMNACA1CA2CA9 | |
| SCHEMBL18530954 | 0.80 | CA2 (0.50) | PPARGCA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
| US-11230517-B2 | Method for aromatic fluorination | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2022-01-25 | — | — | US | disclosed |
| WO-2021155612-A1 | ANTIMALARIAL AGENTS | MERCK SHARP & DOHME CORP. (US) | 2021-08-12 | — | — | WO | disclosed |
| WO-2021155791-A1 | ANTIMALARIAL AGENTS | MERCK SHARP & DOHME CORP. (US) | 2021-08-12 | — | — | WO | disclosed |
| US-10913696-B2 | Method for aromatic fluorination | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-02-09 | — | — | US | disclosed |
| US-20200407292-A1 | METHOD FOR AROMATIC FLUORINATION | CORTEVA AGRISCIENCE LLC | 2020-12-31 | — | — | US | disclosed |
| US-20200239390-A1 | METHOD FOR AROMATIC FLUORINATION | CORTEVA AGRISCIENCE LLC | 2020-07-30 | — | — | US | disclosed |
| EP-3452437-B1 | METHOD FOR AROMATIC FLUORINATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-07-29 | — | — | EP | disclosed |
| US-10654776-B2 | Method for aromatic fluorination | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-05-19 | — | — | US | disclosed |
| US-20190202758-A1 | METHOD FOR AROMATIC FLUORINATION | CORTEVA AGRISCIENCE LLC | 2019-07-04 | — | — | US | disclosed |
| WO-2017192564-A1 | METHOD FOR AROMATIC FLUORINATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407292-A1 | METHOD FOR AROMATIC FLUORINATION | ARSA, AHR, AR | PPARG 799/4885ACHE 2704/4885HTT 504/4885 |
| US-20200239390-A1 | METHOD FOR AROMATIC FLUORINATION | ARSA, AHR, AR | PPARG 772/4885ACHE 3015/4885HTT 578/4885 |
| US-10913696-B2 | Method for aromatic fluorination | ARSA, AHR, AR | PPARG 799/4885ACHE 2704/4885HTT 504/4885 |
| US-11230517-B2 | Method for aromatic fluorination | ARSA, AHR, AR | PPARG 799/4885ACHE 2704/4885HTT 504/4885 |
| US-20190202758-A1 | METHOD FOR AROMATIC FLUORINATION | ARSA, AHR, SNRPF | PPARG 838/4885ACHE 2562/4885HTT 514/4885 |
| US-10654776-B2 | Method for aromatic fluorination | ARSA, AHR, SNRPF | PPARG 838/4885ACHE 2562/4885HTT 514/4885 |
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | PPARG 4667/4885ACHE 4866/4885HTT 4632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.