SCHEMBL1532691

SCHEMBL1532691

Cc1cccc(OS(=O)(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.53
PPARG P37231 1/20 0.53
ACHE P22303 2/20 0.52
HTT P42858 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
ALDH1A1 P00352 2/20 0.43
F2 P00734 1/20 0.43
GAA P10253 3/20 0.41
KMT2A Q03164 1/20 0.41
GLA P06280 1/20 0.41
STS P08842 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17456561 0.98 LMNA (0.52) LMNAPPARGACHEHTTTDP1
SCHEMBL9664445 0.85 CA1 (0.60) PPARGCA1CA2CA9ALDH1A1
SCHEMBL3884174 0.83 ACHE (0.56) LMNAPPARGACHEHTTTDP1
SCHEMBL29468643 0.83 ACHE (0.56) LMNAPPARGACHEHTTTDP1
SCHEMBL4599461 0.82 PPARG (0.58) LMNAPPARGACHEHTTTDP1
SCHEMBL9451450 0.80 CA2 (0.73) PPARGACHECA1CA2CA9
SCHEMBL11164410 0.80 PPARG (0.53) LMNAPPARGACHEHTTTDP1
SCHEMBL14015386 0.80 STS (0.54) LMNAACHEHTTTDP1L3MBTL1
SCHEMBL19568043 0.80 PPARG (0.53) LMNAPPARGACHEHTTTDP1
SCHEMBL4138555 0.79 HTT (0.61) LMNAPPARGHTTTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117126189-A 3-thio-3- (trimethylsilyl) -1-ketone compound, preparation method and application thereof 南京工业大学 2023-11-28 CN claimed
CN-119684180-A Method for synthesizing thio-ester compound 南通大学 2025-03-25 CN disclosed
US-12259397-B2 Biomarkers related to organ function University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2025-03-25 US disclosed
US-20250024837-A1 PESTICIDE SYSTEM BANISH, MICHELE 2025-01-23 US disclosed
CN-117126189-A 3-thio-3- (trimethylsilyl) -1-ketone compound, preparation method and application thereof 南京工业大学 2023-11-28 CN disclosed
CN-116947719-A Synthesis method of visible light two-dimensional alkene nanomaterial synergistic catalysis disulfide compound 南通大学 2023-10-27 CN disclosed
US-20220149436-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2022-05-12 US disclosed
EP-3186245-B1 MAPK INHIBITORS EverBrilliant Pharma Pty Ltd (AU) 2021-06-23 EP disclosed
CN-107074831-B MAPK inhibitors 永辉药业 2020-12-08 CN disclosed
US-20200284805-A1 BIOMARKERS RELATED TO ORGAN FUNCTION UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2020-09-10 US disclosed
US-20110257430-A1 NOVEL COCRYSTALLIZATION APTUIT (KANSAS CITY), LLC (US) 2011-10-20 US disclosed
US-20110251426-A1 SCREENING FOR SOLID FORMS BY ULTRASOUND CRYSTALLIZATION AND COCRYSTALLIZATION USING ULTRASOUND S.S.C.I., INC. (US) 2011-10-13 US disclosed
EP-2292585-A1 Screening for solid forms by ultrasound crystallization and cocrystallization using ultrasound APTUIT (KANSAS CITY), LLC (US) 2011-03-09 EP disclosed
US-20090281195-A1 NOVEL COCRYSTALLIZATION S.S.C.I., INC. (US) 2009-11-12 US disclosed
EP-2012386-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY Mitsubishi Chemical Corporation (JP) 2009-01-07 EP disclosed
US-7452555-B2 Cocrystallization S.S.C.I., INC. (US) 2008-11-18 US disclosed
US-20070287194-A1 Screening For Solid Forms By Ultrasound Crystallization And Cocrystallization Using Ultrasound S.S.C.I., INC 2007-12-13 US disclosed
US-20070088508-A1 Cocrystallization methods APTUIT (WEST LAFAYETTE), LLC 2007-04-19 US disclosed
US-6284473-B1 P-cresol sulfate, a component of urinary myelin basic protein-like material, as a correlate of multiple sclerosis status UAB RESEARCH FOUNDATION 2001-09-04 US disclosed
WO-2001025787-A1 p-CRESOL SULFATE, A COMPONENT OF URINARY MYELIN BASIC PROTEIN-LIKE MATERIAL, AS A CORRELATE OF MULTIPLE SCLEROSIS STATUS UAB RESEARCH FOUNDATION (US) 2001-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250024837-A1 PESTICIDE SYSTEM ACHE, PFAS, FPGS LMNA 3099/4885PPARG 836/4885ACHE 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.