Chloropicrin

Chloropicrin

SCHEMBL195843

O=S(=O)(F)F.O=[N+]([O-])C(Cl)(Cl)Cl

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.69
ALDH1A1 P00352 2/20 0.45
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloropicrin SCHEMBL604956 0.83 TSHR (1.00) TSHRALDH1A1TDP1
Chloropicrin SCHEMBL75169 0.83
Chloropicrin SCHEMBL10611964 0.79
Chloropicrin SCHEMBL28145121 0.79
Chloropicrin SCHEMBL31207791 0.79
Chloropicrin SCHEMBL28064282 0.79 TSHR (0.65) TSHRALDH1A1TDP1
Chloropicrin SCHEMBL28087048 0.75 TSHR (0.44) TSHRALDH1A1
Chloropicrin SCHEMBL4543212 0.73
Chloropicrin SCHEMBL27335999 0.73 TSHR (0.79) TSHRALDH1A1TDP1
Chloropicrin SCHEMBL27768406 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8580710-B2 Pesticidal active mixtures comprising aminothiazoline compounds BASF SE (DE) 2013-11-12 US claimed
EP-2654424-A1 PESTICIDAL ACTIVE MIXTURES COMPRISING PYRAZOLE COMPOUNDS BASF SE (DE) 2013-10-30 EP claimed
WO-2012084670-A1 PESTICIDAL ACTIVE MIXTURES COMPRISING PYRAZOLE COMPOUNDS BASF SE (DE) 2012-06-28 WO claimed
US-20110224075-A1 Pesticidal Active Mixtures Comprising Aminothiazoline Compounds BASF SE (DE) 2011-09-15 US claimed
EP-2273883-A2 PESTICIDAL ACTIVE MIXTURES COMPRISING AMINOTHIAZOLINE COMPOUNDS BASF SE (DE) 2011-01-19 EP claimed
US-20100093531-A1 Pesticidal Mixtures Based on Azolopyrimidinylamines Derivatives and Insecticides BASF SE (DE) 2010-04-15 US claimed
EP-2114159-A2 PESTICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES DERIVATIVES AND INSECTICIDES BASF SE (DE) 2009-11-11 EP claimed
WO-2009118297-A2 PESTICIDAL ACTIVE MIXTURES COMPRISING AMINOTHIAZOLINE COMPOUNDS BASF SE (DE) 2009-10-01 WO claimed
WO-2008092759-A2 PESTICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES DERIVATIVES AND INSECTICIDES BASF SE (DE) 2008-08-07 WO claimed
EP-1952690-A2 Pesticidal mixtures based on triazolopyrimidines and insecticides BASF SE (DE) 2008-08-06 EP claimed
EP-2699563-B3 NOVEL PESTICIDAL PYRAZOLE COMPOUNDS BASF SE (DE) 2024-06-12 EP disclosed
CN-114573573-A Antiparasitic isoxazoline compounds, long-acting injectable formulations containing them, methods and uses thereof 勃林格殷格翰动物保健美国公司 2022-06-03 CN disclosed
CN-109068651-B Antiparasitic isoxazoline compounds, long-acting injectable formulations containing them, methods and uses thereof 勃林格殷格翰动物保健美国公司 2022-03-01 CN disclosed
EP-3763211-A1 ANTIPARASITIC ISOXAZOLINE COMPOUNDS, LONG-ACTING INJECTABLE FORMULATIONS COMPRISING THEM, METHODS AND USES THEREOF Boehringer Ingelheim Animal Health USA Inc. (US) 2021-01-13 EP disclosed
US-20200038370-A1 ANTIPARASITIC ISOXAZOLINE COMPOUNDS, LONG-ACTING INJECTABLE FORMULATIONS COMPRISING THEM, METHODS AND USES THEREOF Boehringer Ingelheim Animal Health USA Inc. (US) 2020-02-06 US disclosed
WO-2007135029-A1 INSECTICIDAL METHODS USING 4-AMINO-5-CHLORO-THIENO[2,3-D]-PYRIMIDINE COMPOUNDS BASF SE (DE) 2007-11-29 WO disclosed
WO-2007118896-A1 O-CARBOXYMETHYL OXIME ETHER COMPOUNDS FOR COMBATING ARTHROPOD PESTS BASF SE (DE) 2007-10-25 WO disclosed
WO-2007113119-A1 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST BASF SE (DE) 2007-10-11 WO disclosed
WO-2007104726-A1 QUINOLINE DERIVATIVES AND THEIR USE AS PESTICIDES BASF SE (DE) 2007-09-20 WO disclosed
WO-2007100165-A1 NEW CRYSTALLINE MODIFICATIONS AND SOLVATE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-09-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100093531-A1 Pesticidal Mixtures Based on Azolopyrimidinylamines Derivatives and Insecticides DDT, INMT, PNMT TSHR 3457/4885ALDH1A1 2185/4885TDP1 1787/4885
US-20110224075-A1 Pesticidal Active Mixtures Comprising Aminothiazoline Compounds CBR3, AOC3, MT-CO3 TSHR 671/4885ALDH1A1 2692/4885TDP1 3736/4885
US-20200038370-A1 ANTIPARASITIC ISOXAZOLINE COMPOUNDS, LONG-ACTING INJECTABLE FORMULATIONS COMPRISING THEM, METHODS AND USES THEREOF IL17A, MMP17, MMP1 TSHR 1865/4885ALDH1A1 2913/4885TDP1 4596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.