Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 9/20 | 0.42 |
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687185 | 0.72 | RAB9A (0.48) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL5324725 | 0.70 | ALDH1A1 (0.50) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL23360634 | 0.69 | NPC1 (0.46) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9465324 | 0.69 | RAB9A (0.53) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10417258 | 0.68 | ABCB11 (0.60) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL13283703 | 0.67 | PTGS1 (0.50) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2074140 | 0.66 | HSD17B10 (0.51) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL18741279 | 0.66 | RAB9A (0.46) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL18320425 | 0.66 | NPC1 (0.53) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2087933 | 0.65 | MAPK1 (0.54) | MAPK1MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3454897-A1 | BICYCLIC FUSED PYRAZOLE DERIVATIVES FOR THE TREATMENT OF RSV | Georgia State University Research Foundation, Inc. (US) | 2019-03-20 | — | — | EP | disclosed |
| WO-2017196982-A1 | BICYCLIC FUSED PYRAZOLE DERIVATIVES FOR THE TREATMENT OF RSV | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2017-11-16 | — | — | WO | disclosed |