Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19588483 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL19590924 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL19590922 | 0.83 | PIN1 (0.43) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL19588479 | 0.76 | NPC1 (0.45) | ALDH1A1MAPTPKMPOLBCYP2C19 | |
| SCHEMBL9390734 | 0.73 | KMT2A (0.62) | ALDH1A1MAPTHTTHSD17B10RAB9A | |
| SCHEMBL17525779 | 0.71 | KDM4E (0.53) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL17525748 | 0.69 | RAB9A (0.73) | ALDH1A1MAPTHTTCYP2C19CYP2D6 | |
| SCHEMBL17525711 | 0.68 | DRD4 (0.50) | CYP2D6PIN1HRH1LMNARAB9A | |
| SCHEMBL4653824 | 0.68 | CYP2C19 (0.71) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL13543173 | 0.68 | ALDH1A1 (0.61) | ALDH1A1MAPTPKMHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815814-B2 | Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives | Obschestvo S Ogranichennoi Otvetstvennostiyu “Pharmenterprises” (RU) | 2017-11-14 | — | — | US | disclosed |