Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19588483 | 0.86 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTPKMPIN1 | |
| SCHEMBL19590925 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTPKMPIN1 | |
| SCHEMBL19590922 | 0.80 | PIN1 (0.43) | ALDH1A1KDM4EMAPTPKMPIN1 | |
| SCHEMBL28967239 | 0.77 | GSK3A (0.64) | ALDH1A1MAPTPOLBGSK3AGSK3B | |
| SCHEMBL19588479 | 0.74 | NPC1 (0.45) | ALDH1A1MAPTPKMPOLBCYP2D6 | |
| SCHEMBL13680867 | 0.72 | ALDH1A1 (0.63) | ALDH1A1KDM4EMAPTPKMABCB1 | |
| SCHEMBL18177326 | 0.70 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTPKMPOLB | |
| SCHEMBL40778 | 0.70 | CMA1 (0.66) | ALDH1A1KDM4EMAPTGSK3AGSK3B | |
| SCHEMBL805155 | 0.70 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTPKMABCB1 | |
| SCHEMBL17525703 | 0.69 | HRH3 (0.39) | PDE4BPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815814-B2 | Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives | Obschestvo S Ogranichennoi Otvetstvennostiyu “Pharmenterprises” (RU) | 2017-11-14 | — | — | US | disclosed |