Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19590922 | 0.83 | PIN1 (0.43) | PIN1PRMT1HSP90AA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19588483 | 0.69 | ALDH1A1 (0.51) | PIN1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19590924 | 0.67 | ALDH1A1 (0.54) | PIN1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4438540 | 0.67 | ALDH1A1 (0.63) | PIN1PRMT1HSP90AA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19590925 | 0.67 | ALDH1A1 (0.50) | PIN1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13680869 | 0.66 | PRMT1 (0.46) | PIN1PRMT1HSP90AA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL22538998 | 0.65 | CHRM1 (0.33) | KMT2A | |
| SCHEMBL13334716 | 0.64 | ABCB1 (0.54) | ALDH1A1KCNH2KDM4EMAPT | |
| SCHEMBL27769702 | 0.64 | PRMT1 (0.44) | PIN1PRMT1HSP90AA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13334633 | 0.64 | ABCB1 (0.48) | PIN1PRMT1ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815814-B2 | Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives | Obschestvo S Ogranichennoi Otvetstvennostiyu “Pharmenterprises” (RU) | 2017-11-14 | — | — | US | disclosed |