Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21217570 | 0.77 | MAPK1 (0.36) | LMNATP53RAB9ARXFP1L3MBTL1 | |
| SCHEMBL21218064 | 0.75 | RAB9A (0.44) | SMN1; SMN2TP53TSHRRAB9ARXFP1 | |
| SCHEMBL21218027 | 0.75 | ALDH1A1 (0.40) | SMN1; SMN2TSHRRXFP1L3MBTL1MEN1 | |
| SCHEMBL22085071 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRRXFP1MEN1KMT2A | |
| SCHEMBL23416897 | 0.74 | CYP1A2 (0.42) | LMNASMN1; SMN2NPC1RAB9ARXFP1 | |
| SCHEMBL23416909 | 0.74 | PORCN (0.58) | TRPA1CYP2D6 | |
| SCHEMBL19626366 | 0.74 | PORCN (0.42) | TRPA1TRPV4 | |
| SCHEMBL23974592 | 0.73 | TSHR (0.57) | LMNASMN1; SMN2TSHRRXFP1KDM4E | |
| SCHEMBL19590941 | 0.73 | KMT2A (0.39) | SMN1; SMN2L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL10114429 | 0.72 | MAPK1 (0.63) | LMNASMN1; SMN2TP53RXFP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815838-B2 | Methods and compositions for treating pain | HYDRA BIOSCIENCES, INC. (US) | 2017-11-14 | — | — | US | disclosed |