Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22085071 | 0.80 | SMN1; SMN2 (0.46) | KMT2AMEN1MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL21217570 | 0.78 | MAPK1 (0.36) | KMT2AMEN1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL19472255 | 0.77 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1HPGDNPSR1KDM4E | |
| SCHEMBL20030198 | 0.77 | TRPA1 (0.56) | KMT2AMEN1SMN1; SMN2ALDH1A1TRPA1 | |
| SCHEMBL21218027 | 0.76 | ALDH1A1 (0.40) | KMT2AMEN1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL21218064 | 0.76 | RAB9A (0.44) | KMT2AMEN1MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL19590910 | 0.76 | ALDH1A1 (0.45) | KMT2AMEN1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL21935695 | 0.74 | PORCN (0.46) | SMN1; SMN2TRPA1HTTTRPV4 | |
| SCHEMBL19590943 | 0.74 | GAA (0.45) | L3MBTL1MAPK1SMN1; SMN2CYP2D6CYP1A2 | |
| SCHEMBL19036794 | 0.74 | ALDH1A1 (0.39) | KMT2AMEN1L3MBTL1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815838-B2 | Methods and compositions for treating pain | HYDRA BIOSCIENCES, INC. (US) | 2017-11-14 | — | — | US | disclosed |