Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16729160 | 0.85 | ALOX15 (0.52) | ALOX15KDM4EHPGDALDH1A1RAB9A | |
| SCHEMBL19592644 | 0.83 | NPC1 (0.56) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL28660721 | 0.82 | ALOX15 (0.62) | ALOX15HRH3KDM4EHPGDALDH1A1 | |
| SCHEMBL1144575 | 0.81 | DAO (0.58) | ALOX15EIF4A3TBXAS1KDM4EHPGD | |
| SCHEMBL7469548 | 0.80 | KDM4E (0.42) | ALOX15KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL17368519 | 0.77 | ALOX15 (0.72) | ALOX15HRH3KDM4EHPGDALDH1A1 | |
| SCHEMBL27987840 | 0.77 | CA12 (0.50) | ALOX15KDM4EHPGDALDH1A1RAB9A | |
| SCHEMBL8251803 | 0.76 | HRH3 (0.54) | ALOX15TBXAS1HRH3KDM4EHPGD | |
| SCHEMBL8985815 | 0.76 | TBXAS1 (0.57) | EIF4A3TBXAS1KDM4EHPGDALDH1A1 | |
| SCHEMBL10420380 | 0.76 | NLRP3 (0.52) | KDM4EHPGDALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815784-B2 | CC-1065 analogs and their conjugates | SYNTARGA B.V. (NL) | 2017-11-14 | — | — | US | disclosed |