SCHEMBL19595693

SCHEMBL19595693

CC1OC1Oc1ccc(-c2ccc(OC3OC3C)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 1/20 0.36
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TYR P14679 1/20 0.33
ESR2 Q92731 1/20 0.33
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
NAAA Q02083 1/20 0.31
NPC1 O15118 1/20 0.30
TP53 P04637 1/20 0.30
MAPK1 P28482 1/20 0.30
CASP3 P42574 1/20 0.30
RAB9A P51151 1/20 0.30
SENP8 Q96LD8 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10945428 0.93 LMNA (0.39) SMN1; SMN2LMNAKDM4EALDH1A1TYR
SCHEMBL11303274 0.84 CA1 (0.50) KDM4EALDH1A1ESR2CA12CA9
SCHEMBL7288725 0.82 SLC6A4 (0.39) SMN1; SMN2LMNACA9
SCHEMBL2020485 0.82 TDP1 (0.44) SMN1; SMN2LMNAKDM4EALDH1A1NPC1
SCHEMBL2020487 0.82 TDP1 (0.44) SMN1; SMN2LMNAKDM4EALDH1A1NPC1
SCHEMBL7332087 0.82 NFE2L2 (0.36) SMN1; SMN2LMNAKDM4EALDH1A1TYR
SCHEMBL7752555 0.81 CA4 (0.40) SMN1; SMN2LMNA
SCHEMBL2282297 0.81 CA4 (0.40) SMN1; SMN2LMNA
SCHEMBL8823952 0.79 LTA4H (0.48) SMN1; SMN2LMNA
SCHEMBL10943120 0.79 HPGD (0.43) SMN1; SMN2LMNAKDM4EALDH1A1TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200172661-A1 FOAMABLE THERMOPLASTIC POLYESTER COPOLYMER SABIC Global Technologies B.V (NL) 2020-06-04 US claimed
US-20190185619-A1 POLYESTER-BASED POLYMERS HAVING IMPROVED HYDROLYTIC STABILITY SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-06-20 US claimed
EP-3455276-A1 POLYESTER-BASED POLYMERS HAVING IMPROVED HYDROLYTIC STABILITY SABIC Global Technologies B.V. (NL) 2019-03-20 EP claimed
WO-2017194337-A1 POLYESTER-BASED POLYMERS HAVING IMPROVED HYDROLYTIC STABILITY SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-11-16 WO claimed
US-20200172661-A1 FOAMABLE THERMOPLASTIC POLYESTER COPOLYMER SABIC Global Technologies B.V (NL) 2020-06-04 US disclosed
EP-3635028-A1 FOAMABLE THERMOPLASTIC POLYESTER COPOLYMER SABIC Global Technologies B.V. (NL) 2020-04-15 EP disclosed
US-20190185619-A1 POLYESTER-BASED POLYMERS HAVING IMPROVED HYDROLYTIC STABILITY SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-06-20 US disclosed
WO-2018224461-A1 FOAMABLE THERMOPLASTIC POLYESTER COPOLYMER SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-12-13 WO disclosed