Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GRN | P28799 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1960906 | 0.79 | ADRB1 (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28566083 | 0.78 | KMT2A (0.40) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL13721462 | 0.76 | KDM4E (0.52) | ALDH1A1KMT2AKDM4EGRNSORT1 | |
| SCHEMBL377165 | 0.76 | KDM4E (0.44) | ALDH1A1SMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL16834262 | 0.76 | P2RX7 (0.46) | KDM4EPGK1PGK2 | |
| SCHEMBL19029855 | 0.73 | PGK1 (0.36) | MAPK1KDM4EPGK1PGK2L3MBTL1 | |
| SCHEMBL755699 | 0.71 | TDP1 (0.47) | ALDH1A1POLBKDM4ELMNA | |
| SCHEMBL16521125 | 0.71 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2POLBMAPK1RAB9A | |
| SCHEMBL1960610 | 0.70 | SMN1; SMN2 (0.35) | SMN1; SMN2PGK1PGK2SYKL3MBTL1 | |
| SCHEMBL47899 | 0.70 | CYP1A2 (0.44) | ALDH1A1SMN1; SMN2MEN1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011066898-A1 | ELECTRONIC DEVICE CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-06-09 | — | — | WO | disclosed |