SCHEMBL1960906

SCHEMBL1960906

CC(C)(C)c1cccc(C(c2cccc(OC(=O)O)n2)c2cccc(C(C)(C)C)n2)n1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 1/20 0.33
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1959613 0.79 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2
SCHEMBL13720624 0.78 KDM4E (0.48) ADRB1ALDH1A1
SCHEMBL377165 0.74 KDM4E (0.44) ALDH1A1SMN1; SMN2
SCHEMBL16834486 0.73 PGK1 (0.38) ALDH1A1
SCHEMBL28566083 0.72 KMT2A (0.40) ALDH1A1
SCHEMBL16834262 0.70 P2RX7 (0.46)
SCHEMBL6223869 0.70 KDM4E (0.44) ALDH1A1
SCHEMBL755699 0.69 TDP1 (0.47) ALDH1A1
SCHEMBL18952265 0.68 ADORA2A (0.39) ALDH1A1
SCHEMBL16712252 0.68 GRN (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011066898-A1 ELECTRONIC DEVICE CONTAINING METAL COMPLEXES MERCK PATENT GMBH (DE) 2011-06-09 WO disclosed