SCHEMBL508665

SCHEMBL508665

C=C(C)C(=O)N(CC(O)COCCC[SiH2]C(O[Si](C)(C)C)O[Si](C)(C)C)CC(O)COCCC[SiH2]C(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL509336 0.84 ZDHHC20 (0.33)
Methacrylic Acid SCHEMBL2125330 0.81 USP2 (0.38)
SCHEMBL331867 0.81 TSHR (0.38)
SCHEMBL509069 0.79
SCHEMBL35420 0.78 USP2 (0.32)
SCHEMBL30386461 0.77 TSHR (0.38)
SCHEMBL508743 0.77 USP2 (0.31)
SCHEMBL508664 0.77 USP2 (0.31)
SCHEMBL30306612 0.76 USP2 (0.47)
SCHEMBL1960031 0.75 MAPT (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4514596-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
EP-4657145-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
EP-4657144-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
US-20250223392-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC (CH) 2025-07-10 US claimed
US-12286501-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2025-04-29 US claimed
US-20240254269-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC. (CH) 2024-08-01 US claimed
US-11926689-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2024-03-12 US claimed
US-20220380509-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC. (CH) 2022-12-01 US claimed
US-20120139138-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2012-06-07 US claimed
US-8163206-B2 Method for making silicone hydrogel contact lenses NOVARTIS AG (CH) 2012-04-24 US claimed
EP-2432808-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS Novartis AG (CH) 2012-03-28 EP claimed
US-20120029111-A1 AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF ALCON INC. (CH) 2012-02-02 US claimed
WO-2012016097-A2 AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF NOVARTIS AG (CH) 2012-02-02 WO claimed
US-20110133350-A1 METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES ALCON INC. (CH) 2011-06-09 US claimed
WO-2010133680-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS NOVARTIS AG (CH) 2010-11-25 WO claimed
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS ALCON INC. (CH) 2010-11-25 US claimed
US-20100258961-A1 Method for making silicone hydrogel contact lenses ALCON INC. (CH) 2010-10-14 US claimed
US-7214809-B2 (Meth)acrylamide monomers containing hydroxy and silicone functionalities JOHNSON & JOHNSON VISION CARE, INC. (US) 2007-05-08 US claimed