SCHEMBL19600400

SCHEMBL19600400

CC1(C)c2ccccc2-c2ccc(-c3ccc4c5c(cccc35)Oc3cc(-c5cccc6ccccc56)ccc3-4)cc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
MAPK1 P28482 1/20 0.40
ATM Q13315 1/20 0.40
ENPP1 P22413 2/20 0.36
ENPP3 O14638 1/20 0.36
CHRNA1 P02708 1/20 0.34
CHRNG P07510 1/20 0.34
CHRNB1 P11230 1/20 0.34
CHRNB2 P17787 1/20 0.34
SLC6A2 P23975 1/20 0.34
CHRNB4 P30926 1/20 0.34
SLC6A4 P31645 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
SLC6A3 Q01959 1/20 0.34
CHRND Q07001 1/20 0.34
MCL1 Q07820 1/20 0.33
ACMSD Q8TDX5 1/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19600433 0.94 KDM4E (0.46) KDM4EMAPK1ATMENPP1ENPP3
SCHEMBL19600422 0.94 KDM4E (0.37) KDM4EMAPK1ATMPDK2
SCHEMBL17265413 0.91 KDM4E (0.35) KDM4EMAPK1ATMENPP1ENPP3
SCHEMBL25843054 0.91 KDM4E (0.41) KDM4EMAPK1ATMPDK2
SCHEMBL25875723 0.89 PDK2 (0.37) KDM4EMAPK1ATMPDK2
SCHEMBL25875592 0.89 MAPK1 (0.35) KDM4EMAPK1ATMENPP1ENPP3
SCHEMBL25843053 0.87 MAPK1 (0.53) KDM4EMAPK1ATMPDK2
SCHEMBL22969554 0.86 KDM4E (0.47) KDM4EMAPK1ATM
SCHEMBL25859512 0.86 MAPK1 (0.43) KDM4EMAPK1ATMENPP1ENPP3
SCHEMBL25868886 0.86 KDM4E (0.39) KDM4EMAPK1ATMPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023120714-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-06-29 WO disclosed
US-10573825-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 US disclosed
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10573825-B2 Compound and organic light-emitting device including the same CRY1, CRY2, AOX1 KDM4E 2074/4885MAPK1 2174/4885ATM 2475/4885
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, AOX1 KDM4E 2074/4885MAPK1 2174/4885ATM 2475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.