SCHEMBL19600433

SCHEMBL19600433

CC1(C)c2ccccc2-c2ccc(-c3ccc4c5c(cccc35)Oc3cc(-c5ccc6c(c5)Oc5cccc7cccc-6c57)ccc3-4)cc21

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
MAPK1 P28482 1/20 0.46
ATM Q13315 1/20 0.46
TYMS P04818 1/20 0.34
PDK2 Q15119 3/20 0.31
ENPP3 O14638 1/20 0.30
ENPP1 P22413 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19600422 0.95 KDM4E (0.37) KDM4EMAPK1ATMPDK2
SCHEMBL19600400 0.94 KDM4E (0.40) KDM4EMAPK1ATMPDK2ENPP3
SCHEMBL25843053 0.93 MAPK1 (0.53) KDM4EMAPK1ATMTYMSPDK2
SCHEMBL25875723 0.90 PDK2 (0.37) KDM4EMAPK1ATMPDK2
SCHEMBL22969554 0.90 KDM4E (0.47) KDM4EMAPK1ATMTYMS
SCHEMBL25843054 0.90 KDM4E (0.41) KDM4EMAPK1ATMPDK2
SCHEMBL25875592 0.88 MAPK1 (0.35) KDM4EMAPK1ATMPDK2ENPP3
SCHEMBL25868886 0.87 KDM4E (0.39) KDM4EMAPK1ATMPDK2
SCHEMBL25843165 0.87 MAPK1 (0.51) KDM4EMAPK1ATMTYMSPDK2
SCHEMBL17265413 0.86 KDM4E (0.35) KDM4EMAPK1ATMENPP3ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573825-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 US disclosed
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10573825-B2 Compound and organic light-emitting device including the same CRY1, CRY2, AOX1 KDM4E 2074/4885MAPK1 2174/4885ATM 2475/4885
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, AOX1 KDM4E 2074/4885MAPK1 2174/4885ATM 2475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.