Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prenylhydroquinone SCHEMBL7036748 | 0.83 | HTT (0.64) | PTGS1PTGS2HTTPTPN1ALDH1A1 | |
| Prenylhydroquinone SCHEMBL5823293 | 0.76 | HTT (0.59) | PTGS1PTGS2HTTPTPN1ALDH1A1 | |
| Geroquinol SCHEMBL29929565 | 0.73 | ALOX5 (0.57) | PTPN1ALOX5ALOX15 | |
| Geroquinol SCHEMBL557012 | 0.73 | ALOX5 (0.57) | PTPN1ALOX5ALOX15 | |
| Geroquinol SCHEMBL557013 | 0.73 | ALOX5 (0.57) | PTPN1ALOX5ALOX15 | |
| SCHEMBL16435130 | 0.73 | PTPN1 (0.51) | PTGS1PTPN1ALOX5ALOX15EGFR | |
| SCHEMBL31536036 | 0.72 | ALOX5 (0.59) | PTPN1ALOX5ALOX15 | |
| SCHEMBL8017471 | 0.72 | ALOX5 (0.59) | PTPN1ALOX5ALOX15 | |
| Geranylgeranylhydroquinone SCHEMBL8025990 | 0.72 | ALOX5 (0.59) | PTPN1ALOX5ALOX15 | |
| SCHEMBL2943955 | 0.72 | ALOX5 (0.59) | PTPN1ALOX5ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10376476-B2 | Panicein compounds, compositions and uses thereof | UNIVERSITE NICE SOPHIA ANTIPOLIS (FR) | 2019-08-13 | — | — | US | disclosed |
| US-20180200200-A1 | PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-07-19 | — | — | US | disclosed |
| US-20180200200-A1 | PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-07-19 | — | — | US | disclosed |
| US-20170326076-A1 | PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-11-16 | — | — | US | disclosed |
| US-20170326076-A1 | PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170326076-A1 | PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF | ABCC1, ABCB1, SLC47A1 | PTGS1 871/4885PTGS2 1253/4885HTT 3273/4885 |
| US-10376476-B2 | Panicein compounds, compositions and uses thereof | ABCC1, ABCB1, SLC47A1 | PTGS1 871/4885PTGS2 1253/4885HTT 3273/4885 |
| US-20180200200-A1 | PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF | ABCC1, ABCB1, SLC47A1 | PTGS1 871/4885PTGS2 1253/4885HTT 3273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.