Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.44 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL17666594 | 0.98 | ALDH1A1 (0.46) | ALDH1A1TSHRFGFR4BBOX1LMNA | |
| Acrylamide SCHEMBL126949 | 0.94 | ALDH1A1 (0.50) | ALDH1A1TSHRFGFR4BBOX1KMT2A | |
| Acrylamide SCHEMBL26087327 | 0.94 | ALDH1A1 (0.50) | ALDH1A1TSHRFGFR4BBOX1KMT2A | |
| Acrylamide SCHEMBL454374 | 0.92 | ALDH1A1 (0.52) | ALDH1A1TSHRFGFR4BBOX1KMT2A | |
| Acrylic Acid SCHEMBL1356182 | 0.92 | LMNA (0.48) | ALDH1A1TSHRBBOX1LMNAKMT2A | |
| Acrylamide SCHEMBL28223917 | 0.90 | ALDH1A1 (0.46) | ALDH1A1TSHRFGFR4BBOX1KMT2A | |
| Acrylamide SCHEMBL27666497 | 0.90 | ALDH1A1 (0.46) | ALDH1A1TSHRFGFR4BBOX1KMT2A | |
| Acrylamide SCHEMBL2111288 | 0.90 | ALDH1A1 (0.46) | ALDH1A1TSHRFGFR4BBOX1LMNA | |
| Acrylamide SCHEMBL28014415 | 0.90 | ALDH1A1 (0.46) | ALDH1A1TSHRFGFR4BBOX1KMT2A | |
| Acrylic Acid SCHEMBL27587559 | 0.89 | LMNA (0.50) | ALDH1A1TSHRBBOX1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040209023-A1 | Coated paperboards and paperboard containers having improved tactile and bulk insulation properties | FORT JAMES CORPORATION | 2004-10-21 | — | — | US | claimed |
| US-6740373-B1 | Coated paperboards and paperboard containers having improved tactile and bulk insulation properties | FORT JAMES CORPORATION | 2004-05-25 | — | — | US | claimed |
| US-20240016723-A1 | SOLID DETERGENT COMPOSITION | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2024-01-18 | — | — | US | disclosed |
| EP-4257114-A1 | SOLID CLEANING AGENT COMPOSITION | Osaka Organic Chemical Industry Ltd. (JP) | 2023-10-11 | — | — | EP | disclosed |
| CN-110475536-B | Hydrogel cosmetic composition having color change with time and comprising solid having flexibility by gamma ray irradiation | 蔻诗曼嘉韩国股份公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-114867555-A | Method for producing microcapsule | 花王株式会社 | 2022-08-05 | — | — | CN | disclosed |
| CN-106821790-B | Hair cosmetic composition | 朋友株式会社 | 2021-09-28 | — | — | CN | disclosed |
| CN-112739316-A | Skin cleanser composition | 株式会社漫丹 | 2021-04-30 | — | — | CN | disclosed |
| CN-108273478-B | Formaldehyde removal composition and product | 李怀玉 | 2021-03-02 | — | — | CN | disclosed |
| CN-108102028-B | Water-in-water amphoteric polyacrylamide emulsion and preparation method thereof | 山东诺尔生物科技有限公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-105997546-B | Body wash composition | 日油株式会社 | 2020-07-14 | — | — | CN | disclosed |
| CN-101730518-A | Highly charged microcapsule | AQUEA SCIENT CORP | 2010-06-09 | — | — | CN | disclosed |
| US-20100036062-A1 | Polyether-Modified Organopolysiloxane, Diorganopolysiloxane-Polyether Block Copolymer, Their Production Methods, and Cosmetic Preparation | DOW TORAY CO., LTD. (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-2022812-A1 | POLYETHER-MODIFIED ORGANOPOLYSILOXANE, DIORGANOPOLYSILOXANE-POLYETHER BLOCK COPOLYMER, THEIR PRODUCTION METHODS, AND COSMETIC PREPARATION | Dow Corning Toray Co., Ltd. (JP) | 2009-02-11 | — | — | EP | disclosed |
| US-20080261845-A1 | SKIN CLEANSING COMPOSITIONS | KAO CORPORATION (JP) | 2008-10-23 | — | — | US | disclosed |
| EP-1982692-A2 | Skin cleansing compositions comprising cationic polymer or polyvinylpyrrolidone | Kao Corporation (JP) | 2008-10-22 | — | — | EP | disclosed |
| US-7037347-B2 | Pretreatment agents for acidic hair dyes | MANDOM CORPORATION (JP) | 2006-05-02 | — | — | US | disclosed |
| US-20040045099-A1 | Pretreatment agents for acidic hair dyes | MANDOM CORPORATION (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1302195-A1 | PRETREATMENT AGENTS FOR ACIDIC HAIR DYES | Mandom Corporation (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-5747014-A | HAIR TREATMENT COSMETICS, ANIONIC SURFACTANTS FOR GELS, EMULSIONS AND THICKENERS | L'OREAL (FR) | 1998-05-05 | — | — | US | disclosed |