Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Acrylamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.33 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.50 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL26087327 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRFGFR4BBOX1KMT2A | |
| Acrylamide SCHEMBL454374 | 0.98 | ALDH1A1 (0.52) | ALDH1A1TSHRFGFR4BBOX1KMT2A | |
| Acrylamide SCHEMBL28223917 | 0.96 | ALDH1A1 (0.46) | ALDH1A1TSHRFGFR4BBOX1KMT2A | |
| Acrylamide SCHEMBL28014415 | 0.96 | ALDH1A1 (0.46) | ALDH1A1TSHRFGFR4BBOX1KMT2A | |
| Acrylamide SCHEMBL2111288 | 0.96 | ALDH1A1 (0.46) | ALDH1A1TSHRFGFR4BBOX1KMT2A | |
| Acrylamide SCHEMBL27666497 | 0.96 | ALDH1A1 (0.46) | ALDH1A1TSHRFGFR4BBOX1KMT2A | |
| Acrylic Acid SCHEMBL1960206 | 0.94 | ALDH1A1 (0.44) | ALDH1A1TSHRFGFR4BBOX1KMT2A | |
| Acrylamide SCHEMBL29256419 | 0.94 | ALDH1A1 (0.44) | ALDH1A1TSHRFGFR4BBOX1KMT2A | |
| Acrylic Acid SCHEMBL626059 | 0.92 | BBOX1 (0.49) | ALDH1A1TSHRFGFR4BBOX1KMT2A | |
| Acrylic Acid SCHEMBL3247699 | 0.92 | BBOX1 (0.49) | ALDH1A1TSHRFGFR4BBOX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2601 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4382172-B1 | COMPOSITION FOR PERMANENT SHAPING OF HUMAN HAIR | KAO GERMANY GMBH (DE) | 2026-03-11 | — | — | EP | claimed |
| EP-3402574-B1 | PERSONAL CARE COMPOSITIONS | COLGATE PALMOLIVE CO (US) | 2026-02-04 | — | — | EP | claimed |
| WO-2025096272-A1 | FABRIC AND HOME CARE COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2025-05-08 | — | — | WO | claimed |
| EP-4547194-A1 | COSMETIC FORMULATIONS COMPRISING STABLE HOMOGENEOUS AQUEOUS SUSPENSION OF BIOPOLYMERS | 11584022 Canada Inc. (CA) | 2025-05-07 | — | — | EP | claimed |
| EP-4549541-A1 | FABRIC AND HOME CARE COMPOSITION | The Procter & Gamble Company (US) | 2025-05-07 | — | — | EP | claimed |
| CN-119894483-A | Cosmetic preparation comprising a stable homogeneous aqueous suspension of a biopolymer | 11584022加拿大有限公司 | 2025-04-25 | — | — | CN | claimed |
| EP-4048749-B1 | COMPOSITION AND METHOD FOR DIELECTRIC CMP | CMC MAT LLC (US) | 2025-01-08 | — | — | EP | claimed |
| US-12151011-B2 | Composition for delaying and dyeing grey hair | PORTILLO ROSADO ROSA MARIA (DO) | 2024-11-26 | — | — | US | claimed |
| CN-118717580-A | Composition for improving surface active foam quality of male shampoo product and preparation method thereof | 广州极男化妆品有限公司 | 2024-10-01 | — | — | CN | claimed |
| WO-2024144568-A1 | ALKALINE CLEANING PRODUCT | ECZACIBASI TUKETIM URUNLERI SANAYI VE TICARET ANONIM SIRKETI (TR) | 2024-07-04 | — | — | WO | claimed |
| WO-1996005373-A1 | IMPROVEMENTS IN OR RELATING TO APPLICATION OF MATERIAL TO A SUBSTRATE | CHEMISOLV LIMITED (GB) | 1996-02-22 | — | — | WO | claimed |
| CN-1102658-A | Screen transparent electrostatic eliminating liquid | LIU FUSHENG (CN) | 1995-05-17 | — | — | CN | claimed |
| EP-0536580-A1 | Application of enzymes and flocculants for enhancing the freeness of paper making pulp | NALCO CHEMICAL COMPANY (US) | 1993-04-14 | — | — | EP | claimed |
| US-5187219-A | For creping cellulosic webs; tissue manufacturing | NALCO CHEMICAL COMPANY (US) | 1993-02-16 | — | — | US | claimed |
| US-5169497-A | Application of enzymes and flocculants for enhancing the freeness of paper making pulp | NALCO CHEMICAL COMPANY (US) | 1992-12-08 | — | — | US | claimed |
| US-5133874-A | Cationic Polymers | AMERICAN CYANAMID COMPANY (US) | 1992-07-28 | — | — | US | claimed |
| EP-0089107-B1 | FILTRATION OF ORGANIC SUSPENSIONS | Ciba Specialty Chemicals Water Treatments Limited (GB) | 1988-10-19 | — | — | EP | claimed |
| EP-0133699-A2 | Compositions for imparting temporary wet strength to paper | AMERICAN CYANAMID COMPANY (US) | 1985-03-06 | — | — | EP | claimed |
| US-4481115-A | TWO-STAGE CONDITIONING WITH POLYELECTROLYTES | ALLIED COLLOIDS LIMITED (GB) | 1984-11-06 | — | — | US | claimed |
| EP-0089107-A2 | Filtration of organic suspensions | Ciba Specialty Chemicals Water Treatments Limited (GB) | 1983-09-21 | — | — | EP | claimed |