SCHEMBL1960424

SCHEMBL1960424

Nc1cnnc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.50
NCF1 P14598 2/20 0.48
DCPS Q96C86 1/20 0.43
KDM4E B2RXH2 6/20 0.43
ALDH1A1 P00352 5/20 0.43
HSD17B10 Q99714 4/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
HPGD P15428 3/20 0.43
ACHE P22303 2/20 0.43
GLA P06280 2/20 0.43
CASP1 P29466 2/20 0.43
CASP7 P55210 2/20 0.43
MAOA P21397 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
CHRM2 P08172 1/20 0.43
ADRA2A P08913 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
CHRM1 P11229 1/20 0.43
NQO2 P16083 1/20 0.43
DRD1 P21728 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30800556 0.98 GPR3 (0.48) GPR3NCF1DCPSKDM4EALDH1A1
Ammonia Solution, Strong SCHEMBL27701708 0.98 GPR3 (0.48) GPR3NCF1DCPSKDM4EALDH1A1
Formic Acid SCHEMBL30452445 0.89 LCK (0.41) GPR3NCF1DCPSKDM4EALDH1A1
SCHEMBL27722231 0.86 HDAC3 (0.41) GPR3NCF1DCPSKDM4EALDH1A1
Trifluoroacetic Acid SCHEMBL29015612 0.83 LCK (0.44) GPR3NCF1DCPSKDM4EALDH1A1
SCHEMBL30800543 0.74 MEN1 (0.40) KDM4EALDH1A1HSD17B10SMN1; SMN2ACHE
SCHEMBL11732569 0.74 LOXL2 (0.52) GPR3KDM4EALDH1A1HSD17B10SMN1; SMN2
SCHEMBL276531 0.73 GPR3 (0.50) GPR3KDM4EALDH1A1HSD17B10SMN1; SMN2
SCHEMBL436407 0.73 GPR3 (0.50) GPR3KDM4EALDH1A1SMN1; SMN2TDP1
SCHEMBL276532 0.73 GPR3 (0.50) GPR3KDM4EALDH1A1SMN1; SMN2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4251617-B1 (AZA)QUINOLINE 4-AMINES DERIVATIVES AS P2X3 INHIBITORS CHIESI FARM SPA (IT) 2025-03-12 EP claimed
CN-100473384-C Pharmaceutical formulations comprising an immune response modifier 3M INNOVATIVE PROPERTIES CO (US) 2009-04-01 CN claimed
CN-101163475-A Aqueous gel formulations containing 1- (2-methylpropyl) -1H-imidazo [4, 5-C ] [1,5] naphthyridin-4-amine TAKEDA PHARMACEUTICAL (JP) 2008-04-16 CN claimed
CN-1610550-A Pharmaceutical formulations comprising an immune response modifier 3M INNOVATIVE PROPERTIES CO (US) 2005-04-27 CN claimed
CN-1523987-A Immune response modifiers for the treatment of periodontal disease 3M创新有限公司 2004-08-25 CN claimed
US-12509474-B2 Inhibitors of complement factors and uses thereof ANNEXON, INC. (US) 2025-12-30 US disclosed
US-12410183-B2 Sars-cov2 main protease inhibitors GILEAD SCIENCES, INC. (US) 2025-09-09 US disclosed
EP-4565574-A1 SARS-COV2 MAIN PROTEASE INHIBITORS GILEAD SCIENCES, INC. (US) 2025-06-11 EP disclosed
CN-119731159-A SARS-CoV2 main proteinase inhibitor 吉利德科学公司 2025-03-28 CN disclosed
US-20250042915-A1 SARS-COV2 MAIN PROTEASE INHIBITORS GILEAD SCIENCES, INC. 2025-02-06 US disclosed
CN-118715231-A Complement factor inhibitors and uses thereof 安尼艾克松股份有限公司 2024-09-27 CN disclosed
US-12091420-B2 SARS-COV2 main protease inhibitors GILEAD SCIENCES, INC. (US) 2024-09-17 US disclosed
US-4886800-A Substituted cinnoline derivatives as CNS depressants ICI AMERICAS INC. (US) 1989-12-12 US disclosed
EP-0328282-A2 Pharmaceutical ICI AMERICAS INC. (US) 1989-08-16 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
CN-86104358-A The preparation method of cinnoline compound 1987-04-01 CN disclosed
EP-0205272-A2 Cinnoline derivatives ICI AMERICAS INC. (US) 1986-12-17 EP disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250042915-A1 SARS-COV2 MAIN PROTEASE INHIBITORS ACE2, TMPRSS2, ACE GPR3 3606/4885NCF1 3538/4885DCPS 708/4885
US-12091420-B2 SARS-COV2 main protease inhibitors ACE2, TMPRSS2, ACE GPR3 3606/4885NCF1 3538/4885DCPS 708/4885
US-12410183-B2 Sars-cov2 main protease inhibitors ACE2, TMPRSS2, ACE GPR3 3606/4885NCF1 3538/4885DCPS 708/4885
US-12509474-B2 Inhibitors of complement factors and uses thereof SSB, UACA, CFH GPR3 3276/4885NCF1 487/4885DCPS 2467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.