Formic Acid

Formic Acid

SCHEMBL30452445

Nc1cnnc2ccccc12.O=CO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.41
MAP2K3 P46734 1/20 0.41
MAP2K6 P52564 1/20 0.41
BTK Q06187 1/20 0.41
MAP3K19 Q56UN5 1/20 0.41
NEK10 Q6ZWH5 1/20 0.41
NCF1 P14598 2/20 0.40
GPR3 P46089 1/20 0.40
ERN1 O75460 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
DCPS Q96C86 1/20 0.36
ACHE P22303 2/20 0.36
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 3/20 0.35
HSD17B10 Q99714 3/20 0.35
GLA P06280 2/20 0.35
ADORA3 P0DMS8 2/20 0.35
CASP1 P29466 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1960424 0.89 GPR3 (0.50) LCKMAP2K3MAP2K6BTKMAP3K19
Hydrochloric Acid SCHEMBL30800556 0.87 GPR3 (0.48) LCKMAP2K3MAP2K6BTKMAP3K19
Ammonia Solution, Strong SCHEMBL27701708 0.87 GPR3 (0.48) LCKMAP2K3MAP2K6BTKMAP3K19
SCHEMBL27722231 0.83 HDAC3 (0.41) LCKMAP2K3MAP2K6BTKMAP3K19
Trifluoroacetic Acid SCHEMBL29015612 0.80 LCK (0.44) LCKMAP2K3MAP2K6BTKMAP3K19
Quinolin-4-Amine SCHEMBL29015439 0.73 NCF1 (0.78) NCF1ERN1KDM4EALDH1A1HPGD
SCHEMBL2009244 0.72 GPR3 (0.44) LCKMAP2K3MAP2K6BTKMAP3K19
Formic Acid SCHEMBL30493146 0.71 KDM4E (0.47) NCF1KDM4EALDH1A1SMN1; SMN2MAOA
Aminacrine SCHEMBL29566014 0.69 HSD17B10 (0.75) LCKMAP2K3MAP2K6BTKMAP3K19
SCHEMBL2008977 0.69 LCK (0.50) LCKMAP2K3MAP2K6BTKMAP3K19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116947903-A Inhibitors of complement factors and uses thereof 安尼艾克松股份有限公司 2023-10-27 CN disclosed
CN-116261564-A Inhibitors of complement factors and uses thereof 安尼艾克松股份有限公司 2023-06-13 CN disclosed