Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.37 |
| ▸ | FURIN | P09958 | 4/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 3/20 | 0.36 |
| ▸ | FNTB | P49356 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GNPAT | O15228 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17326511 | 0.90 | SIRT5 (0.34) | C3AR1FURINSMN1; SMN2KMT2APOLB | |
| SCHEMBL23961922 | 0.89 | FURIN (0.34) | C3AR1FURINSMN1; SMN2KMT2APOLB | |
| SCHEMBL19203658 | 0.88 | FURIN (0.33) | C3AR1FURINSMN1; SMN2KMT2APOLB | |
| SCHEMBL1711520 | 0.85 | C3AR1 (0.44) | C3AR1CTDSP1NOD1FURINFOLH1 | |
| SCHEMBL1711524 | 0.85 | C3AR1 (0.44) | C3AR1CTDSP1NOD1FURINFOLH1 | |
| SCHEMBL18688864 | 0.84 | GNPAT (0.45) | C3AR1CTDSP1NOD1FURINFOLH1 | |
| SCHEMBL28574926 | 0.84 | GNPAT (0.45) | C3AR1CTDSP1NOD1FURINFOLH1 | |
| SCHEMBL26560146 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2KMT2APOLB | |
| SCHEMBL29360312 | 0.83 | NOD1 (0.48) | C3AR1CTDSP1NOD1FURINFOLH1 | |
| SCHEMBL29385639 | 0.82 | C3AR1 (0.45) | C3AR1CTDSP1NOD1FURINFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170326249-A1 | ANTIBODY-DRUG CONJUGATE OF AN ANTI-GLYPICAN-3 ANTIBODY AND A TUBULYSIN ANALOG, PREPARATION AND USES | BRISTOL-MYERS SQUIBB COMPANY | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170326249-A1 | ANTIBODY-DRUG CONJUGATE OF AN ANTI-GLYPICAN-3 ANTIBODY AND A TUBULYSIN ANALOG, PREPARATION AND USES | SERPINA3, B3GAT3, ST3GAL3 | C3AR1 905/4885CTDSP1 2676/4885NOD1 3280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.